Kolchin 0.5 is a medicine used in the treatment and prevention of gout. It reduces inflammation which causes pain, swelling, and other symptoms of gout.... View More
Uses of Kolchin 0.5
Side effects of Kolchin 0.5
How to use Kolchin 0.5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kolchin 0.5 may be taken w... View More
How Kolchin 0.5 works
Kolchin 0.5 reduces inflammation which causes pain, swelling and other symptoms of gout.
What if you forget to take Kolchin 0.5?
If you miss a dose of Kolchin 0.5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Acute gout, Familial Mediterranean Fever, Behcet's disease, Gouty arthritis
Should be taken with food.
Gout Treatment of acute gout flares (Colcrys): 1.2 mg PO at first sign of flare, then 0.6 mg 1 hr later; not to exceed 1.8 mg in 1-hr period Prophylax... View More
Gout <16 years Not recommended >16 years Treatment of acute gout flares: 1.2 mg PO at first sign of flare, then 0.6 mg 1 hr later; not to exceed 1.8... View More
Renal impairment (gout) Mild (CrCl 50-80 mL/min) and moderate (CrCl 30-50 mL/min): Dosage adjustment not necessary; monitor patients for adverse effect... View More
Hypersensitivity; blood dyscrasias, severe renal impairment, pregnancy, debilitated patients; SC/IM admin.
Mode of Action
Colchicine, a phenanthrene derivative, exerts its effect by reducing the inflammatory response to the deposited urate crystals and also by diminishing p... View More
Elderly; GI disease. Cardiac, renal and hepatic impairment; prolonged therapy not recommended; lactation. Lactation: Drug enters breast milk; use wit... View More
>10% Gastrointestinal (GI) effects (eg, diarrhea, nausea, cramping, abdominal pain, vomiting) (26-77%) 1-10% Fatigue (1-4%),Gout (0-4%),Pharyngolar... View More
Pregnancy Category Note
Pregnancy Available human data from published literature on colchicine use in pregnancy over several decades have not identified any drug-associated ri... View More
Reversible malabsorption of vitamin B12 may occur because of ileal mucosal function alteration. Response to CNS depressants and sympathomimetics may inc... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More