Letrozol is used alone or with other treatments, such as surgery or radiation, to treat early breast cancer in postmenopausal women. It can also be used... View More
Uses of Letrozol
Side effects of Letrozol
How to use Letrozol
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letrozol may be taken with... View More
How Letrozol works
Letrozol is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrog... View More
What if you forget to take Letrozol?
If you miss a dose of Letrozol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
May be taken with or without food.
Oral Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Adult: ... View More
Premenopausal women and children; hypersensitivity.
Mode of Action
Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to i... View More
Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in br... View More
Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, ra... View More
Plasma levels reduced by tamoxifen.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More