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Linadi Plus 5002.5mg+500mg

Tablet
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Pacific Pharmaceuticals Ltd.
Generic: Linagliptin + Metformin Hydrochloride
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33.12
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36.00
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Linadi Plus 500.
PregnancyPregnancy
SAFE IF PRESCRIBED
Linadi Plus 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; howeve... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Linadi Plus 500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the b... View More
DrivingDriving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Linadi Plus 500 should be used with caution in patients with kidney disease. Dose adjustment of Linadi Plus 500 may be needed. Please consult your docto... View More
LiverLiver
CAUTION
Linadi Plus 500 should be used with caution in patients with liver disease. Dose adjustment of Linadi Plus 500 may be needed. Please consult your doctor... View More
descriptionMedical Overview

Introduction

Linadi Plus 500 is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serio... View More

Uses of Linadi Plus 500

  • Type 2 diabetes mellitus

Side effects of Linadi Plus 500

Common
  • Diarrhea
  • Nausea
  • Vomiting
  • Upset stomach
  • Headache
  • Nasal congestion (stuffy nose)
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Linadi Plus 500

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Linadi Plus 500 is to be t... View More

How Linadi Plus 500 works

Linadi Plus 500 is a combination of two antidiabetic medicines: Metformin and Linagliptin. Metformin is an antidiabetic medication (biguanide). It works... View More

What if you forget to take Linadi Plus 500?

If you miss a dose of Linadi Plus 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back t... View More

quick tipsQuick Tips
  • Trajenta Duo 2.5mg/500mg Tablet should be taken with food to lower the chances of having an upset stomach.
  • Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar... View More
  • Monitor your blood sugar level regularly while you are taking this medicine.
  • Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as Trajenta Duo 2.5mg/500mg Tabl... View More
descriptionBrief Description

Indication

Type 2 Diabetes mellitus

Administration

Should be taken with meals to reduce the gastrointestinal undesirable effects associated with metformin.

Adult Dose

Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin an... View More

Child Dose

<18 years: Safety and efficacy not established

Renal Dose

Renal impairment Obtain eGFR before starting metformin eGFR <30 mL/min/1.73 m²: Contraindicated eGFR 30-45 mL/min/1.73 m²: Not recommended to initi... View More

Contraindication

Hypersensitivity. Type 1 diabetes, diabetic ketoacidosis or pre-coma, renal failure or dysfunction (CrCl <60 mL/min), hepatic insufficiency, acute alcoh... View More

Mode of Action

Linagliptin: Dipeptidyl peptidase 4 (DPP-4) inhibitor; increases and prolongs incretin hormone activity from glucagon-like peptide-1 (GLP-1) and glucose... View More

Precaution

Monitor for pancreatitis, hypoglycaemia, lactic acidosis, renal impairment. Intravascular administration of iodinated contrast agents. Co-administration... View More

Side Effect

>10% Hypoglycemia (with sulfonylurea) (22.9%) 1-10% Nasopharyngitis (6.3%),Diarrhea (6.3%),Hypoglycemia (without sulfonylurea) (1.4%) Frequency ... View More

Interaction

Linagliptin: Inhibits P-glycoprotein-mediated transport of digoxin (w/ low potency). Increased AUC & Cmax w/ ritonavir. Decreased steady-state AUC & Cma... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More