Rheumatoid arthritis, Osteoarthritis, Acute gouty arthritis, Ankylosing spondylitis, Acute painful shoulder
Should be taken with food.
Oral Ankylosing spondylitis; Osteoarthritis; Rheumatoid arthritis Adult: For symptomatic treatment: 150 mg bid; may adjust subsequent doses based on r... View More
Safety & efficacy not established
Renal impairment: May need dosage reduction. Not recommended in severe renal impairment.
Hypersensitivity. Pregnancy (3rd trimester), treatment of peri-operative pain in CABG surgery .
Mode of Action
Sulindac is a prodrug which undergoes reversible reduction to its active sulfide metabolites. It inhibits prostaglandin synthesis by decreasing cyclooxy... View More
Use at lowest effective dose for shortest duration possible. NSAIDs may increase risk of severe cardiovascular (CV) thrombotic events, myocardial infarc... View More
1-10% GI pain (10%),Constipation (3-9%),Diarrhea (3-9%),Dizziness (3-9%),Dyspepsia (3-9%),Headache (3-9%),Nausea (3-9%),Rash (3-9%),Abdominal cramps (1... View More
Pregnancy Category Note
Pregnancy Category: C; D in 3rd trimester.
Concomittent use with dimethyl sulfoxide may result in peripheral neuropathy. Increased nephrotoxicity with ciclosporin; increased risk of methotrexate ... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More