Introduction
Amynil is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood s... View More
Uses of Amynil
Side effects of Amynil
How to use Amynil
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amynil is to be taken with... View More
How Amynil works
Amynil is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.
What if you forget to take Amynil?
You should skip a dose of Amynil if a meal is skipped, and add a dose of medicine if you eat an extra meal.
Indication
Type 2 DM
Administration
Should be taken with food. Take immediately before or during breakfast, or the 1st main meal of the day. Do not skip meals.
Adult Dose
Oral Type 2 diabetes mellitus Adult: Initially, 1-2 mg daily. May be increased in increments of 1-2 mg at intervals of 1-2 wk. Maintenance: 4 mg daily... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment: 1 mg PO qDay; titrate dose based on fasting blood glucose levels Severe: Contraindicated.
Contraindication
Diabetic ketoacidosis with or without coma.
Mode of Action
Glimepiride stimulates the insulin release from pancreatic beta-cells and reduces glucose output from the liver. It also increases insulin sensitivity a... View More
Precaution
Increased risk of CV mortality. Elderly; hepatic and renal impairment. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in patients w... View More
Side Effect
>10% Hypoglycemia (4-20%) 1-10% Dizziness (1.7%),Asthenia (1.6%),Headache (1.5%),Nausea (1.1%) <1% Allergic skin reactions,Erythema,Morbillifor... View More
Interaction
Salicylates, sulfonamides, chloramphenicol, clarithromycin, coumarin anticoagulants, probenecid, CYP2C9 inhibitors, fibric acid derivatives, disopyramid... View More
SHOW MORE
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More