Introduction
Lola is used in the treatment of liver disease. It protects the liver from harmful chemical substances and improves the functioning of the liver.
Lola is to be taken in dose and duration as prescribed by your doctor. You can take it with or without food. You must take the medicine regularly at a fixed time each day to get the maximum benefit from it. Taking more than recommended doses of this medicine may have harmful effects on your health. The course of the treatment must be completed for better efficacy.
This medicine is generally well tolerated with little or no side effects. However, if you experience any symptoms which you think are due to the medicine, inform your doctor. If you experience any kind of allergic reactions (severe rashes, difficulty in swallowing, shortness of breath, swelling, etc.), you must call for immediate medical help.
Before taking this medicine, you should tell your doctor if you have any kidney disease. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. During the treatment, your doctor may advise regular blood tests to monitor blood creatinine and blood/urine urea levels.
Side effects of Lola
Common
- No common side effects seen
How to use Lola
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Lola may be taken with or without food, but it is better to take it at a fixed time.
How Lola works
Lola is a combination of two amino acids which works by protecting the liver from harmful chemical substances (free radicals), thus preventing liver damage.
Indication
Acute Hepatitis (Viral, non-viral, drug induced), Chronic Hepatitis (with or without hyperammonaemia), Cirrhosis of Liver, Fatty Liver with hyperammonaemia, Hepatic Encephalopathy,
As an adjuvant therapy with all hepatotoxic drugs
Administration
Infusion concentrate
1) Infusion concentrate can be added to any of the conventional intravenous fluids (0.9% sodium chloride, 5% dextrose and Ringer's lactate etc.)
2) The normal dilution rate is 1 ampoule per 100ml of I.V. fluid. However, the dose should not exceed 6 ampoules per 500 ml. infusion. The solution mixtures were stable up to 24 hours.
3) Infusion Rate: 5 g/h at maximum.
Oral
Should be taken during or after meal.
Adult Dose
Injection (Infusion Concentrate)
The recommended dose is up to 20 g (4 ampoules daily).
In case of loss of consciousness (pre-coma) and clouding of consciousness (coma) up to 8 ampoule within 24 hours,depending on the severity of the condition.
Oral
1-2 sachets is dissolved in a large amount of fluid (e.g. in a glass of water or juice) and is taken orally 3 times a day.
Contraindication
Patients with severe renal insufficiency.
Mode of Action
Endogenous Amino Acids, L-Ornithine and L-Aspartate. After administration, it quickly breaks down into L-Ornithine and L-Aspartate. L-Ornithine being a substrate of urea cycle, converts toxic ammonia into non-toxic urea which is eliminated via kidneys, helping the diseased liver to carry out its normal function smoothly (detoxification). The process lowers the elevated level of ammonia in blood (hyperammonaemia) which is a common problem in most of the liver diseases.
L-Aspartate is an essential component of citric acid cycle which liberates energy (ATP), and thus helps in regeneration of damaged liver cells.
Precaution
Caution needed for pregnant and breastfeeding women.
Side Effect
Increased wt; depressed mood, sleep disorder, nervousness, loss of libido, altered mood; headache, migraine; nausea, abdominal pain or distension, flatulence, vomiting; diarrhea, acne; alopecia; back pain; breast discomfort, ovarian cyst, hot flush, uterine/vaginal bleeding including spotting; asthenic conditions, irritability etc.