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5-Fluril 250
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5-Fluril 250250mg/10ml

Injection
rx_reqRequire Prescription
EDCL
Generic: 5-Fluorouracil (5-FU)
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49.50
MRP
55.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with 5-Fluril 250. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
5-Fluril 250 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it... View More
BreastfeedingBreastfeeding
UNSAFE
5-Fluril 250 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
5-Fluril 250 may cause side effects which could affect your ability to drive. 5-Fluril 250 can cause side effects such as nausea and can also produce ad... View More
KidneyKidney
SAFE IF PRESCRIBED
5-Fluril 250 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of 5-Fluril 250 may not be ne... View More
LiverLiver
CAUTION
5-Fluril 250 should be used with caution in patients with liver disease. Dose adjustment of 5-Fluril 250 may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

5-Fluril 250 is used in the treatment of cancers of stomach, colon, rectum, breast, and lungs. It may be used to treat other conditions, as determined b... View More

Uses of 5-Fluril 250

  • Cancer

Side effects of 5-Fluril 250

Common
  • Increased risk of infection
  • Mouth ulcer
  • Vomiting
  • Weakness
  • Nausea
  • Loss of appetite
  • Hair loss
  • Blisters on fingers/feet
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea

How to use 5-Fluril 250

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How 5-Fluril 250 works

5-Fluril 250 is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the ... View More

quick tipsQuick Tips
  • 5-Fluril 250 helps treat cancers of stomach, colon, rectum, breast, and lungs.
  • It is given as an injection into a vein, or as a drip (infusion) into a vein or artery.
  • The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
  • It may cause dizziness and visual changes. Do not drive or do anything requiring concentration until you know how it affects you.
  • Your doctor may regularly monitor your blood cells and liver function during treatment with this medicine.
descriptionBrief Description

Indication

Palliation of malignant neoplasms, Superficial basal cell carcinoma, Oesophageal carcinoma, Carcinoma of Colon, Carcinoma of Breast, Carcinoma of Ovary,... View More

Administration

IV Preparation IV Push: dose/syringe (concentration: 50 mg/mL); max syringe size for IVP is 30 mL syringe and syringe should be <75% full Continuous... View More

Adult Dose

Adult: IV Palliation of malignant neoplasms 12 mg/kg/day (max: 0.8-1g/day) for 3-4 days, if no toxicity occurs, may be followed after 1 day w/ 6 mg/kg o... View More

Child Dose

Child: Safety & efficacy not established.

Renal Dose

Renal impairment: Dose reduction may be required.

Contraindication

Topical application on mucous membranes, exposure to sunlight, hypersensitivity. Depressed bone marrow function, poor nutritional status, potentially se... View More

Mode of Action

Fluorouracil interferes with DNA synthesis by blocking the conversion of deoxyuridylic acid to thymidylic acid. It also interferes with RNA synthesis. T... View More

Precaution

Regular monitoring of blood counts. History of heart disease, hepatic or renal insufficiency, weak or malnourished patients, patients who with history o... View More

Side Effect

1-10% Loss of appetite,Headache,Nausea,Vomiting,Diarrhea,Mucositis,Myelosuppression,Alopecia,Photosensitivity,Hand-foot syndrome,Maculopapular eruption... View More

Pregnancy Category Note

Pregnancy Category: D Risk Summary There are no adequate and well-controlled studies with fluorouracil in pregnant women. Based on its mechanism of ... View More

Interaction

May increase warfarin effects. May reduce response to vaccines; possibility of generalized infection with live vaccines. Action may be modified by allop... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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