Indication
Chew 1-2 tablets after meals and at bedtime as needed (up to 4 times a day).
Do not take more than 16 tablets in 24 hours
Administration
Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.
Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.
Adult Dose
Renal dysfunction, low phosphate diet, prolonged use.
Renal Dose
Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water.
Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.
Mode of Action
After meals and at bedtime as needed. For best results, drink a half glass of water or other liquid after each dose.
Precaution
Hyperacidity, Flatulence, Gastric ulcer, Duodenal ulcer, Gastritis, Stomach distension
Pregnancy Category Note
Diarrhoea, constipation, nausea, vomiting.
Interaction
Hypophosphataemia.