For the treatment of mildly to moderately active ulcerative colitis: The usual dosage in adults is two 400 mg tablets to be taken three times a day for ... View More
Do not give with lactulose or other drugs which lower pH for they prevent release of mesalazine. May decrease digoxin absorption.
Mild to moderate impaired renal or hepatic function (test serum creatinine before treatment, every 3 mth for 1st yr, every 6 mth for next 4 yr, then ann... View More
Anti-inflammatory agent; mesalamine (5-aminosalicylic acid) is the active component of sulfasalazine, but specific MOA is unknown; probably inhibits pro... View More
Ulcerative colitis: Dose is dependent on preparation and brand used. Tablets: 5-15 yr: Acute attack: 15-20 mg/kg (max: 1 g) tid; maintenance of remissio... View More
Mode of Action
May take with or without food.
Ulcerative colitis, Ulcerative proctitis, Crohn's Disease.
Renal impairment: CrCl (ml/min) <20 Avoid.
Pregnancy Category Note
Abdominal pain (4-8%), GI discomfort (4-8%),Headache (7%),Flatulence (1-6%),Nausea (1-6%),Fatigue (3%),Asthenia (3%),Malaise (3%),Weakness (3%),Fever (3... View More
Hypersensitivity to salicylates, aminosalicylates, or any component of the product.- Severe renal impairment (GFR less than 30 mL per minute).- Severe l... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More