Mesala 400 is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarr... View More
Uses of Mesala 400
Side effects of Mesala 400
How to use Mesala 400
Use it as advised by your doctor or check the label for directions before use. Mesala 400 is to be taken with food.
How Mesala 400 works
Mesala 400 is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in t... View More
What if you forget to take Mesala 400?
If you miss a dose of Mesala 400, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More
Ulcerative colitis, Hairy cell leukaemia
Oral Ulcerative colitis Adult: Dose is dependant on preparation and brand used. Acute attack: Initially, up to 4 g daily in 2-4 doses; Maintenance... View More
Oral Ulcerative colitis 5-12 yr: Acute attack: 15-20 mg/kg (max: 1 g) tid; Maintenance of remission: 10 mg/kg (max: 500 mg) 2-3 times daily.
Renal impairment: CrCl (ml/min) Dosage Recommendation <20 Avoid.
Hypersensitivity to mesalazine, salicylates and sulfasalazine. Severe impaired renal (CrCl < 20 ml/min) or hepatic function. Children <2 yr.
Mode of Action
Mesalazine is considered to be the active moiety of sulfasalazine. The mechanism of action is uncertain, but may be due to its ability to inhibit local ... View More
Mild to moderate impaired renal or hepatic function (test serum creatinine before treatment, every 3 mth for 1st yr, every 6 mth for next 4 yr, then ann... View More
Abdominal pain (if new abdominal pain - consider pancreatitis); headache, nausea; flu; fatigue; fever, rash; sore throat; diarrhoea; joint pain; dizzine... View More
Do not give with lactulose or other drugs which lower pH for they prevent release of mesalazine. May decrease digoxin absorption.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More