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Mitomycin10mg

Injection
rx_reqRequire Prescription
Generic: Mitomycin
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Mitomycin may cause excessive drowsiness with alcohol.
PregnancyPregnancy
UNSAFE
Mitomycin is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful ef... View More
BreastfeedingBreastfeeding
CAUTION
Mitomycin should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is ... View More
DrivingDriving
UNSAFE
Mitomycin may cause side effects which could affect your ability to drive. Mitomycin may cause nausea and vomiting and thereby reduce your reaction time... View More
KidneyKidney
CAUTION
Mitomycin should be used with caution in patients with kidney disease. Dose adjustment of Mitomycin may be needed. Please consult your doctor. Use of Mi... View More
LiverLiver
CAUTION
Mitomycin should be used with caution in patients with liver disease. Dose adjustment of Mitomycin may be needed. Please consult your doctor. Use of Mit... View More
descriptionMedical Overview

Introduction

Mitomycin is used in the treatment of certain kinds of cancer of pancreas, breast, lung, and stomach. It can be used alone or in combination with some m... View More

Uses of Mitomycin

  • Pancreatic cancer
  • Breast cancer
  • Non-small cell lung cancer
  • Stomach cancer

Side effects of Mitomycin

Common
  • Anemia (low number of red blood cells)
  • Decreased white blood cell count
  • Increased bleeding tendency
  • Loss of appetite
  • Nausea
  • Vomiting
  • Feeling of discomfort
  • Low blood platelets
  • Weight loss
  • Rash

How to use Mitomycin

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Mitomycin works

Mitomycin is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

quick tipsQuick Tips
  • Inform your doctor if you have any of the following medical conditions: kidney disease; heart disease; or asthma, chronic obstructive pulmonary disease ... View More
  • Before you take mitomycin, inform your doctor if have /are being treated for kidney disease, bleeding disorder or blood disorder.
  • Take precautions as mitomycin can lower the ability of your body to fight infections and the ability of your blood to clot. You may get an infection or ... View More
  • Seek immediate medical attention if you notice any redness, sores, oozing, or other skin changes during or after your treatment with mitomycin. Skin cha... View More
  • Do not drive or operate machinery as mitomycin may cause weakness and lethargy.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
descriptionBrief Description

Indication

Solid tumours, non-invasive bladder cancer, stomach cancer, pancreas cancer, metastatic breast cancer, advanced cervical cancer, anal carcinoma

Administration

IV Preparation Reconstitute with SWI to a concentration of 0.5 mg/mL IV Administration Administer slow IV push by central line only Flush with 5-1... View More

Adult Dose

Intravenous Solid tumours The usual dose is in the range of 4-10 mg (0.06-0.15 mg/kg) given at 1-6 weekly intervals depending on whether other drugs ... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment Serum creatinine >1.7 mg/dL: Avoid use CrCl <10 mL/min: Decrease dose by 25% CAPD: Decrease dose by 25%

Contraindication

Hypersensitivity. Patient w/ platelet counts <100,000/mm3, leukocyte counts <4,000/mm3 or serum creatinine concentration >1.7 mg/dL. Patient w/ substant... View More

Mode of Action

Mitomycin is an antineoplastic antibiotic which is enzymatically reduced to its active metabolite w/in susceptible cells. The active metabolite appears ... View More

Precaution

Patient w/ bone marrow depression, infections including varicella infection. Hepatic or renal impairment. Patient Counselling This drug may cause genera... View More

Side Effect

>10% Hemolytic uremic syndrome (≤15%),Myelosuppression (64%),Nausea/vomiting (14%),Fever (14%) 1-10% Stomatitis (4%),Increased serum creatinine (2%... View More

Interaction

Increased incidence of cardiotoxicity w/ doxorubicin. Potentially Fatal: Increased risk of intravascular haemolysis and renal failure w/ fluorouracil... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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