Myconil 450 is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases ... View More
Uses of Myconil 450
Side effects of Myconil 450
How to use Myconil 450
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Myconil 450 is to be taken empty stomach.
How Myconil 450 works
Myconil 450 is an antibiotic. It works by inactivating a bacterial enzyme (RNA-polymerase) which is required by bacteria to make essential proteins and ... View More
What if you forget to take Myconil 450?
If you miss a dose of Myconil 450, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Tuberculosis, Leprosy, Brucellosis, Meningitis , Legionnaire's disease; Staphylococcal infections
Should be taken on an empty stomach. Best taken on an empty stomach 1 hr before or 2 hr after meals.
Oral Tuberculosis Adult: 10 mg/kg/day or 2-3 times/wk. Max: 600 mg/day. <50 kg: 450 mg daily; >50 kg: 600 mg daily. Leprosy 600 mg once mthly.... View More
Oral Tuberculosis 10–20 mg/kg, max 600 mg for TB q24h With directly observed biweekly therapy, dosage is still 10–20 mg/kg/dose (max 600 mg) twice we... View More
Hypersensitivity to rifampicin or other rifamycins. Patient w/ jaundice. Concurrent use w/ saquinavir/ritonavir therapy.
Mode of Action
Rifampicin suppresses initiation of chain formation for RNA synthesis in susceptible bacteria by binding to the beta subunit of DNA-dependent RNA polyme... View More
Patient w/ history of alcoholism. Hepatic and renal impairment. Elderly, malnourished patients, childn <2 yr. Pregnancy and lactation. Patient Counselli... View More
Facial flushing and itching, w/ or w/o a rash, flu-like syndrome characterised by episodes of fever, chills, headache, dizziness, bone pain, shortness o... View More
May accelerate the metabolism and reduce the effect of drugs that are metabolised by CYP450 enzymes (e.g. quinidine, phenytoin, theophylline). Decreased... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More