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The ACME Laboratories Ltd.
Generic: Nalidixic Acid
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descriptionSafety Advices
Naligram may cause excessive drowsiness with alcohol.
Naligram may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
Naligram is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not h... View More
Naligram does not usually affect your ability to drive.
Naligram should be used with caution in patients with kidney disease. Dose adjustment of Naligram may be needed. Please consult your doctor. Regular mon... View More
Naligram should be used with caution in patients with liver disease. Dose adjustment of Naligram may be needed. Please consult your doctor. Regular moni... View More
descriptionMedical Overview


Naligram is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, ski... View More

Uses of Naligram

  • Bacterial infections

Side effects of Naligram

  • Nausea
  • Diarrhea

How to use Naligram

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and ta... View More

How Naligram works

Naligram is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and ... View More

What if you forget to take Naligram?

If you miss a dose of Naligram, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More

quick tipsQuick Tips
  • Your doctor has prescribed Naligram to cure your infection and improve symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Discontinue Naligram and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
descriptionBrief Description


Lower urinary tract infections, Shigellosis


Should be taken with food.

Adult Dose

Oral Uncomplicated lower urinary tract infections Adult: 1 g 4 times daily for 1-2 wk. Long-term therapy: Reduce daily dose to 2 g. Shigellosis Ad... View More

Child Dose

Oral Uncomplicated lower urinary tract infections Child: >3 mth: 50 mg/kg daily in 4 equally divided doses. Long-term therapy: Reduce dose to 30 mg/kg... View More

Renal Dose

Renal impairment: Reduced doses should be considered.


Hypersensitivity. History of convulsive disorders or porphyria. Infants <3 mth. Severe renal impairment.

Mode of Action

Nalidixic acid is a 4-quinolone antibacterial. It interferes with the replication of bacterial DNA by inhibiting DNA gyrase activity. It acts against gr... View More


Hepatic or moderate renal impairment, severe cerebral arteriosclerosis, G6PD deficiency. Monitor blood counts, renal and hepatic function for treatment ... View More

Side Effect

Nausea, vomiting, diarrhoea, abdominal pain; photosensitivity reactions, allergic rash, urticaria, pruritus; visual disturbances, headache, dizziness or... View More


Absorption reduced by sucralfate, and divalent and trivalent cations e.g. aluminium, calcium, iron, magnesium, zinc. Excretion reduced and plasma concen... View More

Alternative brand for Naligram
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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