Nufa is a prescription medicine used to treat erectile dysfunction (impotence) in men. It works by increasing blood flow to the penis. This helps men to... View More
Uses of Nufa
Side effects of Nufa
How to use Nufa
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nufa may be taken with or ... View More
How Nufa works
Nufa is a phosphodiesterase-5 (PDE-5) inhibitor. It works by relaxing the blood vessels in your penis, thereby increasing blood flow into the penis on s... View More
What if you forget to take Nufa?
If you miss a dose of Nufa, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regu... View More
Erectile dysfunction, Pulmonary arterial hypertension
May be taken with or without food.
Oral Erectile dysfunction Adult: 50 mg about 1 hr before sexual intercourse. May adjust dose depending on penile response. Max: 100 mg/dose and not ... View More
Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Initially, 25 mg.
Hypersensitivity. Patients concurrently or intermittently using organic nitrates in any form.
Mode of Action
Sildenafil inhibits phosphodiesterase type-5 (PDE5) which is responsible for cGMP degradation in the corpus cavernosum. Inhibition of PDE5 increases cGM... View More
Caution when used in patients with anatomical deformation of penis or conditions that may predispose them to priapism (e.g. sickle cell anaemia, myeloma... View More
>10% Headache (7-16%) 1-10% Flushing (4-10%),Epistaxis (8%),Dyspepsia (4-8%),Insomnia (6%),Erythema (5%),Diarrhea (4%),Dizziness (2%),Skin rash (2%... View More
Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the ... View More