Onefix 400 is an antibiotic belonging to the cephalosporin group, which is used to treat a variety of bacterial infections. It is effective in infection... View More
Uses of Onefix 400 Tablet
Side effects of Onefix 400 Tablet
How to use Onefix 400 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Onefix 400 may be taken wi... View More
How Onefix 400 Tablet works
Onefix 400 is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for the... View More
What if you forget to take Onefix 400 Tablet?
If you miss a dose of Onefix 400, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More
Pneumonia, Pharyngitis, Typhoid fever, Susceptible infections , Sinusitis, Otitis media, Tonsillitis, Soft tissue infections, Respiratory tract infectio... View More
May be taken with or without food. May be taken w/ food or milk to reduce GI discomfort.
Acute Bronchitis & Acute Exacerbations of Chronic Bronchitis, Otitis Media, Pharyngitis/Tonsillitis, Uncomplicated Urinary Tract Infections Adult: 200 ... View More
Child: PO 8 mg/kg/day if <50 kg q12–24h For convalescent oral therapy of serious infections, up to 20 mg/kg/day Child over 12 years: Capsule: 200 ... View More
Renal impairment: Dose reduction is necessary. CrCl (ml/min) <20 Max: 200 mg daily.
Hypersensitivity to cephalosporin.
Mode of Action
Cefixime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bac... View More
History of allergy to penicillins; pregnancy, lactation; renal failure; GI disease. Lactation: Unknown whether drug is excreted in milk
>10% Diarrhea (16%) Frequency Not Defined Abdominal pain,Candidiasis,Dizziness,Dyspepsia,Elevated transaminases,Eosinophilia,Erythema multiforme,Fe... View More
Pregnancy Category Note
Pregnancy Available data from published observational studies, case series, and case reports over several decades with cephalosporin use, including cef... View More
Increased concentrations with probenecid. Potentially Fatal: May increase prothrombin time with anticoagulants.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More