Introduction
Aptin M 500 is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious c... View More
Uses of Aptin M 500
Side effects of Aptin M 500
How to use Aptin M 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aptin M 500 is to be taken... View More
How Aptin M 500 works
Aptin M 500 is a combination of two antidiabetic medicines: Metformin and Vildagliptin. Metformin is an anti-diabetic medication (biguanide). It works b... View More
Indication
Type 2 DM
Administration
Should be taken with or just after food.
Adult Dose
Oral Type 2 DM Adults: Based on the patient's current dose of Metformin, Combination of Vildagliptin & Metformin may be initiated at either 50 mg/500... View More
Child Dose
Not recommended in patients <18 years of age
Renal Dose
Renal impairment: This combination should not be used in patients with renal failure or renal dysfunction, e.g. serum creatinine levels > 1.5 mg/dL (>1... View More
Contraindication
This combination is contraindicated in patients with known hypersensitivity to Vildagliptin or Metformin Hydrochloride or to any of the excipients. It i... View More
Mode of Action
Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensiti... View More
Precaution
Lactic acidosis can occur due to Metformin accumulation. If metabolic acidosis is suspected, treatment should be discontinued and the patient should be ... View More
Side Effect
Hypoglycaemia, delayed gastric emptying, nausea and vomiting. Flu-like symptoms, headache and dizziness may occur. Potentially Fatal: Stevens-Johnson... View More
Interaction
Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid m... View More
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More