Oxaliplat 100100mg/vial
Infusion
Healthcare Pharmaceuticals Ltd.
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| Alcohol | CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Oxaliplat 100. Please consult your doctor. |
| Pregnancy | CONSULT YOUR DOCTOR Oxaliplat 100 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe i... View More |
| Breastfeeding | UNSAFE Oxaliplat 100 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. |
| Driving | UNSAFE Oxaliplat 100 may cause side effects which could affect your ability to drive.
Oxaliplatin_name$ treatment may result in an increased risk of dizziness,... View More |
| Kidney | CAUTION Oxaliplat 100 should be used with caution in patients with severe kidney disease. Dose adjustment of Oxaliplat 100 may be needed. Please consult your do... View More |
| Liver | CAUTION Oxaliplat 100 should be used with caution in patients with liver disease. Dose adjustment of Oxaliplat 100 may be needed. Please consult your doctor. |
Introduction
Oxaliplat 100 is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Oxal... View More
Uses of Oxaliplat 100
- Cancer of colon and rectum
Side effects of Oxaliplat 100
- Nausea
- Fatigue
- Anemia (low number of red blood cells)
- Vomiting
- Diarrhea
- Decreased white blood cell count (neutrophils)
- Low blood platelets
- Increased liver enzymes
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Stomatitis (Inflammation of the mouth)
How to use Oxaliplat 100
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Oxaliplat 100 works
Oxaliplat 100 is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and mul... View More
What if you forget to take Oxaliplat 100?
If you miss a dose of Oxaliplat 100, please consult your doctor.
- Oxaliplat 100 is given as an injection into veins under the supervision of a doctor.
Indication
Colorectal cancer, Colon cancer
Administration
IV Preparation Reconstitute by adding 10 mL (for 50 mg vial) or 20 mL (for 100 mg vial) of SWI or D5W. Dilute required amount of reconstituted solution... View More
Adult Dose
Intravenous Advanced colorectal cancer Adult: Day 1: Oxaliplatin 85 mg/m² IV + leucovorin 200 mg/m² IV infused over 2 hr, THEN 5-FU 400 mg/m² IV b... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal Impairment Exposure of unbound platinum tends to increase in renally impaired patients Mild (CrCl 50-80 mL/min): No dosage adjustment required ... View More
Contraindication
Pregnancy. Peripheral neuropathy with functional impairment. Severe renal impairment.
Mode of Action
Oxaliplatin, a platinum-containing complex similar to cisplatin, is an alkylating agent. After intracellular hydrolysis, the platinum compound binds to ... View More
Precaution
Should be administered under the supervision of an experienced cancer chemotherapy physician. Use appropriate precautions for handling and disposal. Mon... View More
Side Effect
>10% Peripheral neuropathy (76%),Anemia (64%),Nausea (64%),Fatigue (61%),Diarrhea (46%),Vomiting (37%),Abdominal pain (31%),Constipation (31%),Thromboc... View More
Interaction
May decrease plasma levels of digoxin. May increase risk of toxicity with nephrotoxic drugs. When administered as sequential infusions, taxane derivativ... View More
Alternative brand for Oxaliplat 100
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More