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Oxaliplat 5050mg/vial

Infusion
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Healthcare Pharmaceuticals Ltd.
Generic: Oxaliplatin
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Oxaliplat 50. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Oxaliplat 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it... View More
BreastfeedingBreastfeeding
UNSAFE
Oxaliplat 50 is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Oxaliplat 50 may cause side effects which could affect your ability to drive. Oxaliplatin_name$ treatment may result in an increased risk of dizziness, ... View More
KidneyKidney
CAUTION
Oxaliplat 50 should be used with caution in patients with severe kidney disease. Dose adjustment of Oxaliplat 50 may be needed. Please consult your doct... View More
LiverLiver
CAUTION
Oxaliplat 50 should be used with caution in patients with liver disease. Dose adjustment of Oxaliplat 50 may be needed. Please consult your doctor.
descriptionMedical Overview

Introduction

Oxaliplat 50 is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Oxali... View More

Uses of Oxaliplat 50

  • Cancer of colon and rectum

Side effects of Oxaliplat 50

Common
  • Nausea
  • Fatigue
  • Anemia (low number of red blood cells)
  • Vomiting
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Low blood platelets
  • Increased liver enzymes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomatitis (Inflammation of the mouth)

How to use Oxaliplat 50

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Oxaliplat 50 works

Oxaliplat 50 is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and mult... View More

What if you forget to take Oxaliplat 50?

If you miss a dose of Oxaliplat 50, please consult your doctor.

quick tipsQuick Tips
  • Oxaliplat 50 is given as an injection into veins under the supervision of a doctor.
descriptionBrief Description

Indication

Colorectal cancer, Colon cancer

Administration

IV Preparation Reconstitute by adding 10 mL (for 50 mg vial) or 20 mL (for 100 mg vial) of SWI or D5W. Dilute required amount of reconstituted solution... View More

Adult Dose

Intravenous Advanced colorectal cancer Adult: Day 1: Oxaliplatin 85 mg/m² IV + leucovorin 200 mg/m² IV infused over 2 hr, THEN 5-FU 400 mg/m² IV b... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment Exposure of unbound platinum tends to increase in renally impaired patients Mild (CrCl 50-80 mL/min): No dosage adjustment required ... View More

Contraindication

Pregnancy. Peripheral neuropathy with functional impairment. Severe renal impairment.

Mode of Action

Oxaliplatin, a platinum-containing complex similar to cisplatin, is an alkylating agent. After intracellular hydrolysis, the platinum compound binds to ... View More

Precaution

Should be administered under the supervision of an experienced cancer chemotherapy physician. Use appropriate precautions for handling and disposal. Mon... View More

Side Effect

>10% Peripheral neuropathy (76%),Anemia (64%),Nausea (64%),Fatigue (61%),Diarrhea (46%),Vomiting (37%),Abdominal pain (31%),Constipation (31%),Thromboc... View More

Interaction

May decrease plasma levels of digoxin. May increase risk of toxicity with nephrotoxic drugs. When administered as sequential infusions, taxane derivativ... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More