Oxalotin is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Oxalotin ... View More
Uses of Oxalotin
Side effects of Oxalotin
How to use Oxalotin
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Oxalotin works
Oxalotin is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multipli... View More
What if you forget to take Oxalotin?
If you miss a dose of Oxalotin, please consult your doctor.
Colorectal cancer, Colon cancer
IV Preparation Reconstitute by adding 10 mL (for 50 mg vial) or 20 mL (for 100 mg vial) of SWI or D5W. Dilute required amount of reconstituted solution... View More
Intravenous Advanced colorectal cancer Adult: Day 1: Oxaliplatin 85 mg/m² IV + leucovorin 200 mg/m² IV infused over 2 hr, THEN 5-FU 400 mg/m² IV b... View More
Safety and efficacy not established
Renal Impairment Exposure of unbound platinum tends to increase in renally impaired patients Mild (CrCl 50-80 mL/min): No dosage adjustment required ... View More
Pregnancy. Peripheral neuropathy with functional impairment. Severe renal impairment.
Mode of Action
Oxaliplatin, a platinum-containing complex similar to cisplatin, is an alkylating agent. After intracellular hydrolysis, the platinum compound binds to ... View More
Should be administered under the supervision of an experienced cancer chemotherapy physician. Use appropriate precautions for handling and disposal. Mon... View More
>10% Peripheral neuropathy (76%),Anemia (64%),Nausea (64%),Fatigue (61%),Diarrhea (46%),Vomiting (37%),Abdominal pain (31%),Constipation (31%),Thromboc... View More
May decrease plasma levels of digoxin. May increase risk of toxicity with nephrotoxic drugs. When administered as sequential infusions, taxane derivativ... View More