Palotic is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to ... View More
Uses of Palotic
Side effects of Palotic
How to use Palotic
Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow... View More
How Palotic works
Palotic is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting... View More
What if you forget to take Palotic?
If you miss a dose of Palotic, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More
Chemotherapy-induced nausea and vomiting, Postoperative nausea and vomiting
Reconstitution: Physically and chemically stable at concentrations of 5 and 30 mcg/ml in glucose 5%, sodium chloride 0.9%, glucose 5% in lactated Ringer... View More
Prevention of Chemotherapy-induced Nausea & Vomiting Intravenous Adult: 0.25 mg IV as a single dose. To be given over 30 sec and 30 minutes before che... View More
Prevention of Postoperative Nausea & Vomiting <18 years: Safety and efficacy not established Prevention of Chemotherapy-induced Nausea & Vomiting <... View More
Renal impairment: Dose adjustment not necessary
History of hypersensitivity.
Mode of Action
Palonosetron is a selective 5-HT3 antagonist that is used in the prevention of acute and delayed emesis in emetogenic cancer chemotherapy regimens.
Patients with intestinal obstruction or ileus. Rapid inj may lead to temporary visual changes e.g. blurred vision. Patients who have or may develop prol... View More
1-10% Prolonged QT interval (up to 5% ),Anxiety,Dizziness,Headache,Weakness,Constipation,Diarrhea,Prutitus,Hyperkalemia,LFT's increased <1% First d... View More
May have additive effect on prolonging QT with drugs e.g. moxifloxacin, erythromycin, antipsychotics and TCAs.
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More