Introduction
Arbium Plus 100/12.50 is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treate... View More
Uses of Arbium Plus 100/12.50
Side effects of Arbium Plus 100/12.50
How to use Arbium Plus 100/12.50
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arbium Plus 100/12.50 may ... View More
How Arbium Plus 100/12.50 works
Arbium Plus 100/12.50 is a combination of two medicines: Losartan and Hydrochlorothiazide, which lowers the blood pressure effectively. Losartan is an a... View More
Indication
Hypertension, Stroke, risk reduction of hypertensive or LVH patients
Adult Dose
Hypertension Initial: 50 mg/12.5 mg PO qDay If dose titrated upward, do not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q1... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment CrCl <30 mL/min: Do not use thiazide-containing products; loop diuretic preferred CrCl >30 mL/min: No dosage adjustment required
Contraindication
Pregnancy, lactation; intravascular volume depletion.
Mode of Action
Hydrochlorothiazide increases renal excretion of sodium and chloride and reduces cardiac load. Losartan is an angiotensin II receptor (type AT1) antagon... View More
Precaution
Existing electrolyte disturbances; hepatic cirrhosis; severe hepatic failure; oedema; elderly (>75 yr); renal impairment; hepatic impairment; diabetes, ... View More
Side Effect
>10% Losartan Fatigue (14%),Hypoglycemia (14%),Chest pain (12%),Cough, incidence higher in previous cough related to ACE therapy (3-11%) 1-10% Los... View More
Interaction
Reduced excretion of lithium; effect of diuretic, natriuretic & other antihypertensive w/ NSAIDs including selective COX-2 inhibitors. Do not co-adminis... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More