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Parixol 180180mcg

Tablet
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ACI Limited
Generic: Pramipexol
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
Parixol 180 may cause excessive drowsiness with alcohol.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Parixol 180 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develo... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Parixol 180 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Pa... View More
DrivingDriving
UNSAFE
Parixol 180 may cause side effects which could affect your ability to drive. Parixol 180 can cause hallucinations (seeing, hearing or feeling things tha... View More
KidneyKidney
CAUTION
Parixol 180 should be used with caution in patients with kidney disease. Dose adjustment of Parixol 180 may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Parixol 180 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Parixol 180 may not be neede... View More
descriptionMedical Overview

Introduction

Parixol 180 is a prescription medicine used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompan... View More

Uses of Parixol 180

  • Parkinson's disease
  • Restless leg syndrome

Side effects of Parixol 180

Common
  • Dizziness
  • Sleepiness
  • Nausea
  • Dryness in mouth
  • Fatigue
  • Hallucination
  • Constipation
  • Peripheral edema

How to use Parixol 180

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Parixol 180 is to be taken... View More

How Parixol 180 works

Parixol 180 works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

quick tipsQuick Tips
  • You have been prescribed Parixol 180 to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
  • It can be taken with or without food. Taking it with food may reduce nausea.
  • For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
  • Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
  • When you first start taking Parixol 180, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy... View More
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.
  • Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
  • Do not stop taking the medication suddenly without talking to your doctor.
descriptionBrief Description

Indication

Parkinson's disease, Restless leg syndrome

Administration

May be taken with or without food. May be taken w/ meals to minimise GI side effects such as nausea.

Adult Dose

Parkinson Disease Immediate-release: 0.125 mg PO q8hr initially; gradually titrated upward at weekly intervals to target range of 1.5-4.5 mg/day PO div... View More

Renal Dose

Parkinson disease Immediate release CrCl >50 mL/min: Dosage adjustment not necessary CrCl 30-50 mL/min: 0.125 mg twice daily initially; not to exceed... View More

Contraindication

Hypersensitivity. Lactation.

Mode of Action

Pramipexole is a nonergot-derivative dopamine receptor agonist which alleviates Parkinsonian motor deficits by directly stimulating postsynaptic dopamin... View More

Precaution

Psychotic disorder, severe CV disease, augmentation (earlier onset, increase and spread of symptoms). Risk of neuroleptic malignant syndrome w/ abrupt w... View More

Side Effect

>10% Somnolence,Dyskinesia,Hallucinations,Insomnia,Dizziness,Postural hypotension,Nausea,Constipation 1-10% (partial list) Abnormal dreams, thought... View More

Interaction

Inhibits active tubular secretion of basic cationic drugs eg, cimetidine. Reduced clearance w/ drugs eliminated by active renal tubular secretion eg, am... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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