Pefla is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin a... View More
Uses of Pefla
Side effects of Pefla
How to use Pefla
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pefla is to be taken with ... View More
How Pefla works
Pefla is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and rep... View More
What if you forget to take Pefla?
If you miss a dose of Pefla, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your reg... View More
Susceptible infections, Gonococcal urethritis, Acute uncomplicated cystitis
Should be taken with food. Take w/ meals.
Oral Susceptible infections Adult: 400 mg bid. Acute uncomplicated cystitis in women; Gonococcal urethritis in men Adult: 800 mg as single dose. ... View More
Renal impairment: Dose reduction may be necessary.
Hypersensitivity to quinolones, children <12 yr, pregnancy, lactation.
Mode of Action
Pefloxacin is a fluoroquinolone antibacterial that exhibits its bactericidal action by inhibition of DNA gyrase and topoisomerase IV which are needed fo... View More
Underlying CNS disease; hepatic disease; renal impairment. Avoid sun exposure, may cause severe sunburn.
Nausea, vomiting, gastric pain, dizziness, insomnia, allergic skin reactions, thrombocytopaenia, leukopenia/neutropenia, photosensitisation, arthropathy... View More
Reduced absorption with antacids, didanosine (DDI), iron salts, pirenzepine, sucralfate, vincristine, zinc salts; increased levels with cimetidine, prob... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More