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Pendoril Plus 4/1.251.25mg+4mg

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Renata Limited
Generic: Indapamide + Perindopril Erbumine
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descriptionSafety Advices
Pendoril Plus 4/1.25 may cause excessive drowsiness with alcohol.
Pendoril Plus 4/1.25 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely pres... View More
Pendoril Plus 4/1.25 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to ... View More
Pendoril Plus 4/1.25 may cause side effects which could affect your ability to drive. Pendoril Plus 4/1.25 usually does not affect alertness but dizzine... View More
Pendoril Plus 4/1.25 should be used with caution in patients with kidney disease. Dose adjustment of Pendoril Plus 4/1.25 may be needed. Please consult ... View More
Pendoril Plus 4/1.25 should be used with caution in patients with liver disease. Dose adjustment of Pendoril Plus 4/1.25 may be needed. Please consult y... View More
descriptionMedical Overview


Pendoril Plus 4/1.25 is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pr... View More

Uses of Pendoril Plus 4/1.25

  • Hypertension (high blood pressure)

Side effects of Pendoril Plus 4/1.25

  • Nausea
  • Diarrhea
  • Stomach pain
  • Constipation
  • Vomiting
  • Headache
  • Vertigo
  • Dizziness
  • Altered vision
  • Numbness
  • Ringing in ear
  • Breathlessness
  • Indigestion
  • Allergic reaction
  • Skin rash
  • Itching
  • Cramps
  • Fatigue

How to use Pendoril Plus 4/1.25

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pendoril Plus 4/1.25 is to... View More

How Pendoril Plus 4/1.25 works

Pendoril Plus 4/1.25 is a combination of two medicines: Perindopril and indapamide which lower blood pressure effectively. Perindopril is an angiotensin... View More

quick tipsQuick Tips
  • You have been prescribed Pendoril Plus 4/1.25 for the treatment of high blood pressure.
  • It also lowers your risk of stroke and heart attack.
  • Take it in the morning with breakfast, to avoid getting up at night to urinate.
  • Pendoril Plus 4/1.25 may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform you doctor about any cough, or throat irritation that doesn't go away.
  • Pendoril Plus 4/1.25 may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mou... View More
  • Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this... View More
  • Do not take Pendoril Plus 4/1.25 if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.
descriptionBrief Description



Adult Dose

Oral Hypertension Adult: 1 tab once daily in the morning.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Avoid use. 30-60 Dose adjustment may be needed


Hypersensitivity. Severe renal impairment (CrCl <30 ml/min), hypokalaemia, severe hepatic impairment or hepatic encephalopathy, history of angioedema as... View More

Mode of Action

Perindopril is an ACE inhibitor, which acts by inhibiting the conversion of angiotensin I to angiotensin II, reducing the activity of the sympathetic ne... View More


Impaired renal function, risk of hypotension and electrolyte imbalance. Regular monitoring of renal function and plasma levels of potassium are recommen... View More

Side Effect

Dry cough, headache, bradycardia, dizziness, asthenia, hypokalaemia and orthostatic hypotension. GI effects such as constipation, dry mouth, nausea, epi... View More


Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin.... View More

Alternative brand for Pendoril Plus 4/1.25
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More