Piol M 500500mg+15mg
Tablet
Opsonin Pharma Limited
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| Alcohol | UNSAFE It is unsafe to consume alcohol with Piol M 500. |
| Pregnancy | CONSULT YOUR DOCTOR Piol M 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the develop... View More |
| Breastfeeding | SAFE IF PRESCRIBED Piol M 500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. |
| Driving | CAUTION Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur. |
| Kidney | CAUTION Piol M 500 should be used with caution in patients with kidney disease. Dose adjustment of Piol M 500 may be needed. Please consult your doctor.
Use of ... View More |
| Liver | CAUTION Piol M 500 should be used with caution in patients with liver disease. Dose adjustment of Piol M 500 may be needed. Please consult your doctor.
Piol M 5... View More |
Introduction
Piol M 500 is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar... View More
Uses of Piol M 500
- Type 2 diabetes mellitus
Side effects of Piol M 500
- Nausea
- Loss of appetite
- Taste change
- Stomach pain
- Diarrhea
- Edema (swelling)
- Weight gain
- Respiratory tract infection
- Bone fracture
- Blurred vision
How to use Piol M 500
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piol M 500 is to be taken ... View More
How Piol M 500 works
Piol M 500 is a combination of two antidiabetic medicines: Pioglitazone and metformin. Pioglitazone is a thiazolidinedione which works by increasing the... View More
- Take it as per the dose and duration prescribed by your doctor.
- Monitor your blood sugar level regularly while you are taking this medicine.
- It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxi... View More
- Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing o... View More
- Inform your doctor if you notice weight gain, shortness of breath, irregular heartbeat, or any abnormal swelling.
Indication
Type 2 DM
Adult Dose
Oral Type 2 diabetes mellitus Adult: Tab contains pioglitazone 15 mg and metformin 500 mg or 850 mg: Initially, 15 mg/500 mg bid or 15 mg/850 mg on... View More
Child Dose
Safety and efficacy not established
Renal Dose
Renal impairment Obtain eGFR before starting metformin eGFR <30 mL/min/1.73 m²: Contraindicated eGFR 30-45 mL/min/1.73 m²: Not recommended to initiat... View More
Contraindication
Renal disease or renal dysfunction (e.g. as suggested by serum creatinine levels >1.5 mg/dl in male, >1.4 mg/dl in females or abnormal creatinine cleara... View More
Mode of Action
Pioglitazone is as a potent and highly selective agonist for the peroxisome proliferator activated receptor-gamma. Activation of these receptors promote... View More
Precaution
Patient w/ oedema, anaemia. Premenopausal, anovulatory women. Pregnancy. Patient Counselling This drug may cause visual disturbance, if affected, do not... View More
Side Effect
>10% Lower limb edema (2.9-11.3%),Upper respiratory infection (12-16) 1-10% Weight gain (2.9-6.7%),Diarrhea (4.8-5.8%),Nausea (3.6-5.8%),Urinary tr... View More
Interaction
Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid m... View More
Alternative brand for Piol M 500
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More