Synovia Pharma PLC
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Consuming alcohol with Pleflacine does not cause any harmful side effects.
Information regarding the use of Pleflacine during pregnancy is not available. Please consult your doctor.
Pleflacine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pleflacine may cause side effects which could affect your ability to drive.
There is limited information available on the use of Pleflacine in patients with kidney disease. Please consult your doctor.
Pleflacine should be used with caution in patients with liver disease. Dose adjustment of Pleflacine may be needed. Please consult your doctor.
Pleflacine is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, s... View More
Uses of Pleflacine
- Bacterial infections
Side effects of Pleflacine
How to use Pleflacine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pleflacine is to be taken ... View More
How Pleflacine works
Pleflacine is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing an... View More
What if you forget to take Pleflacine?
If you miss a dose of Pleflacine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to you... View More
- Your doctor has prescribed Pleflacine to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Discontinue Pleflacine and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Susceptible infections, Gonococcal urethritis, Acute uncomplicated cystitis
Should be taken with food. Take w/ meals.
Oral Susceptible infections Adult: 400 mg bid. Acute uncomplicated cystitis in women; Gonococcal urethritis in men Adult: 800 mg as single dose. ... View More
Renal impairment: Dose reduction may be necessary.
Hypersensitivity to quinolones, children <12 yr, pregnancy, lactation.
Mode of Action
Pefloxacin is a fluoroquinolone antibacterial that exhibits its bactericidal action by inhibition of DNA gyrase and topoisomerase IV which are needed fo... View More
Underlying CNS disease; hepatic disease; renal impairment. Avoid sun exposure, may cause severe sunburn.
Nausea, vomiting, gastric pain, dizziness, insomnia, allergic skin reactions, thrombocytopaenia, leukopenia/neutropenia, photosensitisation, arthropathy... View More
Reduced absorption with antacids, didanosine (DDI), iron salts, pirenzepine, sucralfate, vincristine, zinc salts; increased levels with cimetidine, prob... View More
Alternative brand for Pleflacine
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More