Pregalex is a medicine used to relieve pain caused by nerve damage (neuropathic pain) due to diabetes, shingles (herpes zoster infection), spinal cord i... View More
Uses of Pregalex
Side effects of Pregalex
How to use Pregalex
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Pregalex may be taken with or without food, but i... View More
How Pregalex works
Pregalex is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus... View More
What if you forget to take Pregalex?
If you miss a dose of Pregalex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your ... View More
Anxiety, Fibromyalgia, Post herpetic Neuralgia, Partial seizures, Pain from diabetic neuropathy, Neuropathic pain associated with spinal cord injury
May be taken with or without food.
Oral Neuropathic pain, Postherpetic Neuralgia Adult: Initially, 150 mg/day, may increase to 300 mg/day after 3-7 days. Max: 600 mg/day after a 7-day i... View More
Safety and efficacy not established
Renal impairment: Haemodialysis: 25-100 mg immediately after each 4-hr haemodialysis session. CrCl (ml/min) Dosage Recommendation 30 to <60 75 mg/day.... View More
Hypersensitivity. Pregnancy, lactation. Driving or working with machines, or do other dangerous activities.
Mode of Action
Pregabalin is an analog of the neurotransmitter GABA. It binds potently to the alpha2-delta subunit resulting in modulation of Ca channels and reduction... View More
Abrupt or rapid discontinuation of Pregabalin may produce some symptoms including insomnia, nausea, headache and diarrhoea. So Pregabalin should be tape... View More
>10% Dizziness (8-45%),Somnolence (4-36%),Peripheral edema (16%),Ataxia (1-20%),Fatigue (5-11%),Xerostomia (1-15%),Weight gain (16%),Tremor (11%),Blurr... View More
May potentiate the effects of lorazepam. Additive CNS depressant effects w/ opiates and benzodiazepines. May increase risk of angioedema w/ ACE inhibito... View More