Introduction
Arnigen 100 is a combination medicine used to treat heart failure. It reduces the risk of hospitalization and death due to long-lasting (chronic) heart ... View More
Uses of Arnigen 100
Side effects of Arnigen 100
How to use Arnigen 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arnigen 100 may be taken w... View More
How Arnigen 100 works
Arnigen 100 is a combination of two medicines: Sacubitril and Valsartan which belong to a class of angiotensin receptor neprilysin inhibitor (ARNI). Thi... View More
Indication
Heart Failure,
Administration
May take with or without food
Adult Dose
Heart Failure Indicated to reduce the risk of cardiovascular death and hospitalization for heart failure (HF) in patients with chronic heart failure (C... View More
Renal Dose
Renal impairment Mild-to-moderate (eGFR ?30 mL/min/1.73 m²): No starting dose adjustment required Severe (eGFR <30 mL/min/1.73 m²): Reduce starting do... View More
Contraindication
Hypersensitivity to any component History of angioedema related to previous ACE inhibitor or ARB therapy Coadministration of neprilysin inhibitors (eg... View More
Mode of Action
Combination is an angiotensin receptor-neprilysin inhibitor (ARNi) Sacubitril: Neprilysin inhibitor; neprilysin is responsible for degradation of atria... View More
Precaution
Can cause fetal harm when administered to a pregnant woman; use of drugs that act on the renin-angiotensin system during the second and third trimesters... View More
Side Effect
>10% Hypotension (18%) Hyperkalemia (12%) 1-10% Cough (9%) Dizziness (6%) Orthostasis (2.1%) Falls (1.9%) <1% Angioedema, all patients (0.5... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More