Probac125mg/5ml
Powder for Suspension
Silva Pharmaceuticals Ltd.
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| Alcohol | SAFE Consuming alcohol with Probac does not cause any harmful side effects. |
| Pregnancy | SAFE IF PRESCRIBED Probac is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there ... View More |
| Breastfeeding | SAFE IF PRESCRIBED Probac is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not har... View More |
| Driving | NOT RELEVANT Not relevant, as Probac is intended for use in hospitalised patients. |
| Kidney | CONSULT YOUR DOCTOR There is limited information available on the use of Probac in patients with kidney disease. Please consult your doctor. |
| Liver | CONSULT YOUR DOCTOR There is limited information available on the use of Probac in patients with liver disease. Please consult your doctor. |
Introduction
Probac is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (e.g. pneumonia), ear, thro... View More
Uses of Probac
- Bacterial infections
Side effects of Probac
- Rash
- Vomiting
- Allergic reaction
- Increased liver enzymes
- Nausea
- Injection site reaction
- Diarrhea
How to use Probac
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Probac works
Probac is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to sur... View More
What if you forget to take Probac?
If you miss a dose of Probac, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
- Your doctor has prescribed Probac to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to ... View More
- Discontinue Probac and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your st... View More
- Avoid consuming alcohol while taking Probac as it may cause increased side effects.
Indication
Pharyngitis, Acute otitis media, Lyme disease, Susceptible infections, Sinusitis, Otitis media, Skin and skin structure infections,Tonsillitis, Respirat... View More
Administration
Tab: May be taken with or without food. Oral susp: Should be taken with food. IV Preparation Direct injection: reconstitute in 8 mL (for 750-mg via... View More
Adult Dose
Pharyngitis/Tonsillitis 250 mg PO q12hr for 10 days Acute Bacterial Maxillary Sinusitis 250 mg PO q12hr for 10 days Acute Bacterial Exacerbation... View More
Child Dose
Children: PO 20–30 mg/kg/day q12h For bone and joint infections, up to 100 mg/kg/day IV, IM 100–150 mg/kg/day q8h
Renal Dose
Renal impairment: Patients undergoing haemodialysis should receive an additional 750-mg dose after each dialysis; those undergoing continuous peritoneal... View More
Contraindication
Hypersensitivity to cephalosporins.
Mode of Action
Cefuroxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in b... View More
Precaution
Severe renal impairment; pregnancy, lactation; hypersensitivity to penicillins. Lactation: Drug excreted in breast milk; use with caution
Side Effect
>10% Diarrhea (4-11%; depends on duration) 1-10% Decreased hemoglobin or hematocrit (10%),Eosinophilia (7%),Nausea or vomiting (3-7%),Vaginitis (<5... View More
Pregnancy Category Note
Pregnancy Available data from published epidemiologic studies, case series, and case reports over several decades in pregnant women have not establishe... View More
Interaction
May enhance the nephrotoxic effect of strong-acting diuretics (e.g. furosemide) and aminoglycosides. May enhance the effect of oral anticoagulants. May ... View More
Alternative brand for Probac
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More