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Progil 50
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Progil 5050mg

Tablet
rx_reqRequire Prescription
ACI Limited
Generic: Voriconazole
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descriptionSafety Advices
AlcoholAlcohol
UNSAFE
It is unsafe to consume alcohol with Progil 50.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Progil 50 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in... View More
BreastfeedingBreastfeeding
CONSULT YOUR DOCTOR
Progil 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingDriving
UNSAFE
Progil 50 may cause side effects which could affect your ability to drive. Progil 50 may cause blurring of vision or uncomfortable sensitivity to light ... View More
KidneyKidney
SAFE IF PRESCRIBED
Progil 50 is safe to use in patients with kidney disease. No dose adjustment of Progil 50 is recommended.
LiverLiver
CAUTION
Progil 50 should be used with caution in patients with liver disease. Dose adjustment of Progil 50 may be needed. Please consult your doctor. Regular mo... View More
descriptionMedical Overview

Introduction

Progil 50 belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat a wide range of fungal infe... View More

Uses of Progil 50

  • Severe fungal infections

Side effects of Progil 50

Common
  • Abnormal liver function tests
  • Hallucination
  • Slow heart rate
  • Altered vision
  • Headache
  • Nausea
  • Rash
  • Vomiting

How to use Progil 50

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Progil 50 is to be taken e... View More

How Progil 50 works

Progil 50 is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.... View More

quick tipsQuick Tips
  • Your doctor has prescribed Progil 50 to cure your infection and improve symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It should be taken one hour before or one hour after a meal.
  • Do not take indigestion remedies (antacids) within two hours of taking Progil 50.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin... View More
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description

Indication

Candidemia, Deep tissue Candida infections, Invasive aspergillosis, Scedosporiosis and Fusariosis

Administration

Should be taken on an empty stomach. Take at least 1 hr before or after meals. Infuse IV over 1-2 hr, not to exceed 3 mg/kg/hr

Adult Dose

Adult Invasive Aspergillosis, Candidemia, Serious Fungal Infections 6 mg/kg IV q12hr for first 24 hours, then 4 mg/kg IV q12hr or 200 mg PO q12hr ... View More

Child Dose

<12 years: Safety and efficacy not established Child >12 years Invasive Aspergillosis, Candidemia, Serious Fungal Infections 6 mg/kg IV q12hr for f... View More

Contraindication

Hypersensitivity. Co-admin w/ CYP3A4 substrates, terfenadine, astemizole, cisapride, pimozide, quinidine, rifampicin, carbamazepine, long-acting barbitu... View More

Mode of Action

Voriconazole is a triazole antifungal agent which inhibits cytochrome P450-dependent enzymes thereby inhibiting ergosterol synthesis in fungal cell memb... View More

Precaution

Patient w/ potentially proarrhythmic conditions, risk for acute pancreatitis. Correct electrolyte disturbances e.g. hypokalaemia, hypomagnesaemia and hy... View More

Side Effect

>10% Visual changes (photophobia, color changes, increased or decreased visual acuity, or blurred vision occur in 21%) 1-10% Tachycardia,Hypertensi... View More

Interaction

Increased prothrombin time w/ oral anticoagulants. May increase plasma concentrations of ciclosporin and tacrolimus, long-acting opiates (e.g. oxycodone... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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