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It is not known whether it is safe to consume alcohol with Puri-Nethol. Please consult your doctor.
Puri-Nethol is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it ... View More
Puri-Nethol is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Puri-Nethol does not usually affect your ability to drive.
Puri-Nethol should be used with caution in patients with kidney disease. Dose adjustment of Puri-Nethol may be needed. Please consult your doctor.
Puri-Nethol should be used with caution in patients with liver disease. Dose adjustment of Puri-Nethol may be needed. Please consult your doctor. Inform... View More
Puri-Nethol is used in the treatment of blood cancer. It shows its working by decreasing the number of red blood cells, which is produced by the body. ... View More
Uses of Puri-Nethol
- Blood cancer
Side effects of Puri-Nethol
- Decreased white blood cell count (neutrophils)
- Intestinal ulcer
- Anemia (low number of red blood cells)
- Increased bilirubin in the blood
- Low blood platelets
- Increased transaminase level in blood
- Loss of appetite
How to use Puri-Nethol
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Puri-Nethol may be taken w... View More
How Puri-Nethol works
Puri-Nethol interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growi... View More
- Puri-Nethol is used for the treatment of cancer of the blood.
- Take it with or without food.
- Do not drive or do anything requiring concentration until you know how it affects you.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Acute lymphatic leukaemia, Crohn's disease
Should be taken on an empty stomach. Best taken on an empty stomach 1 hr before or 2 hr after meals. Ensure adequate fluid intake.
Acute Lymphatic Leukemia Induction: 2.5 mg/kg PO qDay; usually 100-200 mg PO qDay in average adult (other agents preferred) May increase by 5 mg/kg/d... View More
Acute Lymphatic Leukemia Starting dose: 1.25-2.5 mg/kg (50-75 mg/m²) PO qDay Maintenance: 1.5-2.5 mg/kg PO qDay in combination with methotrexate
Renal Impairment: Dosage may need to be reduced.
Pregnancy and lactation. Prior resistance to mercaptopurine or thioguanine; severe liver disease; severe bone marrow suppression.
Mode of Action
Mercaptopurine is a purine antagonist which is converted intracellularly into its active nucleotides, including thioinosinic acid. The nucleotides inhib... View More
Hepatic or renal dysfunction; monitor hepatic function periodically. Mercaptopurine is potentially carcinogenic. Thiopurine S-methyl transferase (TPMT) ... View More
>10% Elevated LFT's (15%) 1-10% Nausea (10%),Vomiting (10%),Stomatitis (3-10%),Thrombocytopenia (3-10%),Rash (1-3%),Diarrhea (1-3%),Dizziness (1-3%... View More
Anticoagulant action of warfarin may be inhibited by mercaptopurine. Enhanced toxicity with myelosuppressive drugs. Potentially Fatal: Effects enhanc... View More
Alternative brand for Puri-Nethol
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More