Purinol 100 is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which ca... View More
Uses of Purinol 100
Side effects of Purinol 100
How to use Purinol 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Purinol 100 is to be taken... View More
How Purinol 100 works
Purinol 100 is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
What if you forget to take Purinol 100?
If you miss a dose of Purinol 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More
Adult: PO Gout; Hyperuricaemia Mild: 100 mg/day PO initially; increased weekly to 200-300 mg/day Moderate to severe: 100 mg/day PO initially; incre... View More
May inhibit the metabolism of mercaptopurine and azathioprine; reduce dose of mercaptopurine and azathioprine when given w/ allopurinol. May increase ef... View More
Ensure adequate fluid intake. Prophylactically with an anti-inflammatory or colchicine for at least 1 mth. Withdraw immediately when sensitivity (skin r... View More
Allopurinol is an inhibitor of the enzyme xanthine oxidase which converts hypoxanthine to xanthine then uric acid. The reduced production of uric acid r... View More
Mode of Action
Administration Should be taken with food. Take immediately after meals.
Hyperuricaemia, Uric acid nephropathy, Cancer therapy-induced hyperuricaemia, Gout, Recurrent renal stones
Renal impairment: Haemodialysis: Administer dose after session or administer 50% supplemental dose. CrCl (ml/min) 10-20 200 mg daily. <3 100 mg da... View More
Pregnancy Category Note
1-10% Rash (1.5%),Nausea (1.3%),Renal failure (1.2%),Vomiting (1.2%) Frequency Not Defined Amblyopia,Arthralgias,Blood dyscrasias,Bronchospasm,Card... View More
Hypersensitivity; acute attack of gout.