It is unsafe to consume alcohol with PXYJ.
CONSULT YOUR DOCTOR
PXYJ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some... View More
PXYJ is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
PXYJ may cause side effects which could affect your ability to drive.
As there is no reason why you cannot continue driving between courses of PXYJ but ... View More
SAFE IF PRESCRIBED
PXYJ is safe to use in patients with kidney disease. No dose adjustment of PXYJ is recommended.
However, talk to your doctor if you have any underlying ... View More
PXYJ should be used with caution in patients with liver disease. Dose adjustment of PXYJ may be needed. Please consult your doctor.
Use of PXYJ is not r... View More
PXYJ is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.
It is given as an injectio... View More
Uses of PXYJ
- Breast cancer
- Non-small cell lung cancer
- Pancreatic cancer
Side effects of PXYJ
- Low blood platelets
- Upper respiratory tract infection
- Urinary tract infection
- Anemia (low number of red blood cells)
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Hair loss
- Decreased blood pressure
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Decreased white blood cell count (neutrophils)
How to use PXYJ
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How PXYJ works
PXYJ is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows... View More
- PXYJ is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
- It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.
- Do not take PXYJ if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
- Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
- Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.
Ovarian carcinoma, Breast cancer, Lung cancer, Kaposi's sarcoma
Reconstitution: Paclitaxel must be diluted before infusion. It can be diluted in 0.9% sodium chloride inj, 5% dextrose inj, 5% dextrose and 0.9% sodium ... View More
Adult: Primary treatment (in combination with cisplatin or carboplatin): 135 mg/m2 infused over 24 hr followed by cispla... View More
Safety and efficacy not established
History of hypersensitivity (especially macrogol glycerol ricinolate). Patients with baseline neutropenia of <1500 cells/mm3 (<1000 cells/mm3 for kaposi... View More
Mode of Action
Paclitaxel promotes microtubule formation by enhancing the action of tubulin dimers, stabilising existing microtubules and preventing their disassembly,... View More
Bone marrow suppression during therapy. Monitor cardiac function if conduction abnormalities result. Premedicaton (with corticosteroid, antihistamine an... View More
Neutropenia (78-100%),Alopecia (55-96%),Anemia (47-96%),Arthralgia/myalgia (93%),Diarrhea (90%),Leukopenia (90%),Nausea/vomiting (9-88%),Opportuni... View More
Myelosuppression was more profound when given after cisplatin than with the alternate sequence (e.g., paclitaxel before cisplatin). CYP2C8 inducers e.g.... View More