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Opsonin Pharma Limited
Generic: Quinine Dihydrochloride
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descriptionMedical Overview


Malaria, Nocturnal leg cramps

Adult Dose

Intravenous Malaria Adult: As diHCl: Initially, 20 mg/kg to max 1.4 g over 4 hr w/ maintenance infusion started after 8 hr. Maintenance infusions: 1... View More

Child Dose

Intravenous Malaria Child: <5 mg/kg/hr by slow IV infusion.

Renal Dose

Renal impairment: Severe: Reduce maintenance dose to 5-7 mg/kg of quinine salt 8 hrly.


Hypersensitivity to quinine, mefloquine or quinidine. Patients w/ nocturnal leg cramps; prolonged QT interval, tinnitus or optic neuritis, myasthenia gr... View More

Mode of Action

Quinine is a cinchona alkaloid and a 4-methanolquinoline. It rapidly acts on blood schizontocide by interfering w/ lysosomal function or nucleic acid sy... View More


Patients w/ cardiac conduction defects, heart block or AF. Pregnancy and lactation. Monitoring Parameters Monitor for signs of cardiotoxicity. Monitor b... View More

Side Effect

<1% Flushing of the skin,Anginal symptoms,Fever,Rash,Pruritus,Hypoglycemia,Epigastric pain,Hemolysis in G6PD deficiency,Thrombocytopenia,Hepatitis,Nigh... View More


Reduced renal clearance of amantadine. Reduced clearance w/ cimetidine. Increased anticoagulant effect of warfarin and other anticoagulants. Reduced pla... View More

Alternative brand for Quins
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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