Ramelta is a prescription medicine used in the treatment of insomnia. It helps to synchronize the body’s biological day-night rhythm. It resolves troubl... View More
Uses of Ramelta
Side effects of Ramelta
How to use Ramelta
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ramelta may be taken with ... View More
How Ramelta works
Ramelta is a melatonin receptor agonist. Ramelta works like melatonin, a chemical messenger in the brain that helps regulate the sleep-wake cycle.
What if you forget to take Ramelta?
If you miss a dose of Ramelta, skip it and continue with your normal schedule. Do not double the dose.
Ramelteon is indicated for the, treatment of insomnia, characterized by difficulty with sleep onset.
Take within 30 min of going to bed. Should not be taken with or immediately after a high-fat meal.
Adult: Tablet 8 mg taken within 30 minutes of going to bed. Total daily dose should not exceed 8 mg.
Safety and efficacy not established
Hypersensitivity Ramelteon is not recommended in patients with severe hepatic impairment. Patients who develop angioedema after treatment with Ramelte... View More
Mode of Action
Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 and MT2 receptors and selectivity over the MT3 receptor. The activ... View More
In rare cases, severe anaphylactic and anaphylactoid reactions have occurred following use of Ramelteon. Angioedema involving the tongue, glottis, or la... View More
Most common adverse reactions (≥3% and more common than with placebo) are: somnolence, dizziness, fatigue, nausea, and exacerbated insomnia.
Rifampin (strong CYP enzyme inducer): Decreases exposure to and effects of ramelteon. Ketoconazole (strong CYP3A4 inhibitor): Increases AUC for ramelt... View More