Rasagil 0.5 is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and sti... View More
Uses of Rasagil 0.5
Side effects of Rasagil 0.5
How to use Rasagil 0.5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rasagil 0.5 may be taken w... View More
How Rasagil 0.5 works
Rasagil 0.5 works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.
May be taken with or without food. Avoid tyramine-rich foods, beverages or dietary supplements & amines (from cough/cold prep).
Parkinson Disease Monotherapy: 1 mg PO qDay Adjunct without levodopa: 1 mg PO qDay Adjunct to levodopa: 0.5 mg PO qDay initially, may increase to 1 m... View More
<18 years: Safety and efficacy not established
Renal impairment: No dosage adjustment required for mild-to-moderate; not studied in severe
Severe hepatic impairment. Concomitant use w/ other MAOIs and pethidine w/in 14 days after discontinuation of therapy; St John's wort.
Mode of Action
Rasagiline is a potent, irreversible monoamine oxidase (MAO)-B selective inhibitor which may cause an increase in extracellular levels of dopamine in th... View More
May cause hypertension (including severe hypertensive syndromes) at recommended doses May exacerbate hypertension; antihypertensive drugs may require d... View More
>10% EPS (dyskinesia/dystonia) (18%) Headache (14%) Nausea (10-12%) 1-10% Postural hypotension (6-9%) Constipation (4-9%) Weight loss (2-9%) A... View More
Increased plasma levels w/ potent CYP1A2 inhibitors (e.g. ciprofloxacin). Increased clearance w/ entacapone. Potentially Fatal: Increased risk of non-s... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More