Rasalet 1 is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and stiff... View More
Uses of Rasalet 1
Side effects of Rasalet 1
How to use Rasalet 1
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rasalet 1 may be taken wit... View More
How Rasalet 1 works
Rasalet 1 works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.
May be taken with or without food. Avoid tyramine-rich foods, beverages or dietary supplements & amines (from cough/cold prep).
Parkinson Disease Monotherapy: 1 mg PO qDay Adjunct without levodopa: 1 mg PO qDay Adjunct to levodopa: 0.5 mg PO qDay initially, may increase to 1 m... View More
<18 years: Safety and efficacy not established
Renal impairment: No dosage adjustment required for mild-to-moderate; not studied in severe
Severe hepatic impairment. Concomitant use w/ other MAOIs and pethidine w/in 14 days after discontinuation of therapy; St John's wort.
Mode of Action
Rasagiline is a potent, irreversible monoamine oxidase (MAO)-B selective inhibitor which may cause an increase in extracellular levels of dopamine in th... View More
May cause hypertension (including severe hypertensive syndromes) at recommended doses May exacerbate hypertension; antihypertensive drugs may require d... View More
>10% EPS (dyskinesia/dystonia) (18%) Headache (14%) Nausea (10-12%) 1-10% Postural hypotension (6-9%) Constipation (4-9%) Weight loss (2-9%) A... View More
Increased plasma levels w/ potent CYP1A2 inhibitors (e.g. ciprofloxacin). Increased clearance w/ entacapone. Potentially Fatal: Increased risk of non-s... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More