Introduction
Repres SR 1.5 is a diuretic (water pill) medicine used to treat hypertension (high blood pressure). This medicine reduces excess fluid levels in the body and treats edema (fluid overload) associated with heart, liver, kidney, or lung disease.
Repres SR 1.5 makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your blood pressure rising up again and increase your risk of heart disease and stroke.
It is important to have your blood pressure checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can eat normally while taking this medicine, but try to reduce your salt intake.
Common side effects of this medicine include headache, nausea, and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, its better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Regular monitoring of kidney function and electrolytes is important while using this medicine.
Uses of Repres SR 1.5
- Hypertension (high blood pressure)
Side effects of Repres SR 1.5
Common
- Dizziness
- Headache
- Fatigue
- Nausea
- Gastrointesinal symptoms
- Muscle cramp
How to use Repres SR 1.5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Repres SR 1.5 may be taken with or without food, but it is better to take it at a fixed time.
How Repres SR 1.5 works
Repres SR 1.5 is a thiazide diuretic. It lowers blood pressure by removing the extra water and certain electrolytes from the body. Over time it also works by relaxing blood vessels and improving blood flow.
What if you forget to take Repres SR 1.5?
If you miss a dose of Repres SR 1.5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Indication
Hypertension, Congestive heart failure
Administration
Should be taken with food.
Adult Dose
Oral
Hypertension
Adult: 1.25-2.5 mg once daily, alone or in conjunction with other antihypertensives.
Oedema
Adult: 2.5 mg once daily increased to 5 mg daily after 1 wk if needed.
Child Dose
Safety & efficacy not established
Contraindication
Anuria, severe hepatic impairment.
Mode of Action
Indapamide enhances excretion of sodium, chloride and water by interfering with the transport of sodium ions across the renal tubular epithelium.
Precaution
Pregnancy, lactation, elderly, renal impairment, fluid or electrolyte imbalance, hyperuricaemia, DM, lupus erythematosus.
Lactation: not known if excreted into breast milk, avoid
Side Effect
1-10%
Hypotension,Palpation,Flushing,Dizziness,Lightheadedness,Vertigo,Headache,Weakness,Restlessness,Drowsiness,Fatigue,Lethargy,Malaise,Anorexia,Nausea/vomiting,Nocturia,Polyuria,Blurred vision,Rhinnorhea,Electrolyte abnormalities,Pruritus,Rash
<1%
Cutaneous vasculitis,Glycosuria,Pancreatitis
Interaction
Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin.
Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.