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Rubicin
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সারা বাংলাদেশ থেকে অর্ডার করা যাবে।

Rubicin20mg/10ml

Injection
rx_reqRequire Prescription
Beacon Pharmaceuticals Ltd.
Generic: Daunorubicin
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Best Price
540.00
MRP
600.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rubicin. Please consult your doctor.
PregnancyPregnancy
CONSULT YOUR DOCTOR
Rubicin is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More
BreastfeedingBreastfeeding
UNSAFE
Rubicin is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
DrivingDriving
UNSAFE
Rubicin may cause side effects which could affect your ability to drive.
KidneyKidney
CAUTION
Rubicin should be used with caution in patients with kidney disease. Dose adjustment of Rubicin may be needed. Please consult your doctor. Use of Rubici... View More
LiverLiver
CAUTION
Rubicin should be used with caution in patients with liver disease. Dose adjustment of Rubicin may be needed. Please consult your doctor. Use of Rubicin... View More
descriptionMedical Overview

Introduction

Rubicin is used for the treatment of blood cancer (leukemia). It works by interfering with the growth of cancer cells, which are eventually destroyed. ... View More

Uses of Rubicin

  • Blood cancer

Side effects of Rubicin

Common
  • Nausea
  • Vomiting
  • Low blood platelets
  • Ulcer
  • Abdominal pain
  • Loss of appetite
  • Decreased white blood cell count
  • Hair loss
  • Fever
  • Decreased blood cells (red cells, white cells, and platelets)
  • Fatigue
  • Anemia (low number of red blood cells)
  • Chills
  • Diarrhea
  • Mucosal inflammation
  • Febrile neutropenia
  • Stomatitis (Inflammation of the mouth)
  • Breathing problems

How to use Rubicin

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Rubicin works

Rubicin is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

quick tipsQuick Tips
  • You must undergo careful examination of functioning of the heart as daunorubicin is known to cause life-threatening heart problems due to damage to hear... View More
  • Daunorubicin should be used cautiously is elderly, children, and patients with high blood pressure (manifest arterial hypertension) due to increased ris... View More
  • You may be frequently examined for complete blood-count (blood cells, proteins, hemoglobin), kidney, liver and heart function before and during the cour... View More
  • Tell your doctor if you have had, have an ongoing or scheduled radiation therapy or X-ray of the chest area. Daunorubicin increases the risk of reaction... View More
  • You should be monitored for worsening of infections and development of life-threatening infections (e.g. viral infections like herpes zoster) as daunoru... View More
  • Liposomal preparation of daunorubicin is not recommended for use in children <18 years.
  • Before starting daunorubicin treatment, make sure that you are free from any side effects of previous chemotherapy (inflammation of the mouth, abnormal ... View More
  • Both partners should take extreme care to avoid pregnancy while on daunorubicin therapy and consult your doctor if you get to know that you are pregnant... View More
descriptionBrief Description

Indication

Acute leukaemia, AIDS-related Kaposi's sarcoma

Administration

IV Preparation Reconstitute 20 mg vial with 4 mL SWI to a final concentration of 5 mg/mL IV Administration Vesicant, never administer IM or SC I... View More

Adult Dose

Acute Nonlymphocytic Leukemia In combination with cytarabine 100 mg/m²/day IV for 7 days first course, for 5 days subsequent courses <60 years old:... View More

Child Dose

Acute Nonlymphocytic Leukemia <2 years old or <0.5 m² BSA: 1 mg/kg IVP qWeek >2 years old or >0.5 m² BSA: 25 mg/m² IVP qWeek Acute Lymphocytic Leu... View More

Renal Dose

Renal Impairment >3 mg/dL serum creatinine: Administer 50% regular dose

Contraindication

Heart failure. Pregnancy, lactation.

Mode of Action

Daunorubicin forms a stable complex with DNA and interferes with the nucleic acid synthesis. It is a cell-cycle nonspecific agent, but its cytotoxic eff... View More

Precaution

Regular blood count and ECG monitoring; elderly, children. Hepatic or renal impairment may increase risk of toxicity. Pre-existing cardiac disease and p... View More

Side Effect

>10% Nausea,Vomiting,Arrhythmias,Discoloration of urine,Alopecia 1-10% Injection site skin flare,Hyperuricemia,GI ulceration,Diarrhea <1% Arryt... View More

Pregnancy Category Note

Pregnancy Category: D Lactation: excretion in milk unknown/not recommended

Interaction

Increased risk of cardiotoxicity when used with cyclophosphamide. Increased risk of hepatic toxicity when used with hepatotoxic drugs e.g. high-dose met... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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