Saplox is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin ... View More
Uses of Saplox
Side effects of Saplox
How to use Saplox
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Saplox may be taken with o... View More
How Saplox works
Saplox is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and re... View More
What if you forget to take Saplox?
If you miss a dose of Saplox, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your re... View More
Chronic bronchitis, Community-acquired pneumonia
May be taken with or without food.
Oral Adult 2 tablets (400 mg) on 1st day as a loading dose, followed by 1 tablet (200 mg) daily as a maintenance dose. Duration of maintenance treat... View More
Renal impairment (Creatinine clearance < 50 ml/min) is 2 tablets (400 mg) taken on the first day as a loading dose. Thereafter, 1 tablet of 200 mg shoul... View More
Hypersensitivity; pregnancy and lactation; children <18 yr.
Mode of Action
Sparfloxacin inhibits the supercoiling activity of DNA gyrase which is an enzyme essential for DNA replication thus promoting the breakage of DNA struct... View More
History of CNS disorders, pseudomembranous colitis, superinfection, severe renal dysfunction, epilepsy, G6PD deficiency, myasthenia gravis, patients wit... View More
Diarrhoea, abdominal pain, nausea, vomiting; jaundice, renal failure, elevation of liver enzymes, BUN and creatinine; anaphylactoid reaction, headache, ... View More
Cations such as aluminum, magnesium, zinc and iron may reduce the bioavailability of sparfloxacin. May increase the plasma concentrations of theophyllin... View More