Secrin 1 is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood... View More
Uses of Secrin 1
Side effects of Secrin 1
How to use Secrin 1
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Secrin 1 is to be taken wi... View More
How Secrin 1 works
Secrin 1 is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.
What if you forget to take Secrin 1?
You should skip a dose of Secrin 1 if a meal is skipped, and add a dose of medicine if you eat an extra meal.
Type 2 DM
Should be taken with food. Take immediately before or during breakfast, or the 1st main meal of the day. Do not skip meals.
Oral Type 2 diabetes mellitus Adult: Initially, 1-2 mg daily. May be increased in increments of 1-2 mg at intervals of 1-2 wk. Maintenance: 4 mg daily... View More
Safety and efficacy not established
Renal impairment: 1 mg PO qDay; titrate dose based on fasting blood glucose levels Severe: Contraindicated.
Diabetic ketoacidosis with or without coma.
Mode of Action
Glimepiride stimulates the insulin release from pancreatic beta-cells and reduces glucose output from the liver. It also increases insulin sensitivity a... View More
Increased risk of CV mortality. Elderly; hepatic and renal impairment. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in patients w... View More
>10% Hypoglycemia (4-20%) 1-10% Dizziness (1.7%),Asthenia (1.6%),Headache (1.5%),Nausea (1.1%) <1% Allergic skin reactions,Erythema,Morbillifor... View More
Salicylates, sulfonamides, chloramphenicol, clarithromycin, coumarin anticoagulants, probenecid, CYP2C9 inhibitors, fibric acid derivatives, disopyramid... View More