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Silinor 100100mg

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Healthcare Pharmaceuticals Ltd.
Generic: Sitagliptin
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descriptionSafety Advices
It is unsafe to consume alcohol with Silinor 100.
Silinor 100 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, t... View More
Silinor 100 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.... View More
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Silinor 100 should be used with caution in patients with kidney disease. Dose adjustment of Silinor 100 may be needed. Please consult your doctor.
Silinor 100 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Silinor 100 may not be neede... View More
descriptionMedical Overview


Silinor 100 is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar le... View More

Uses of Silinor 100

  • Type 2 diabetes mellitus

Side effects of Silinor 100

  • Headache
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
  • Upper respiratory tract infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Silinor 100

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Silinor 100 may be taken w... View More

How Silinor 100 works

Silinor 100 is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood ... View More

What if you forget to take Silinor 100?

If you miss a dose of Silinor 100, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More

quick tipsQuick Tips
  • Silinor 100 should be taken at the same time every day since this helps you remember to take it.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxie... View More
  • Be careful while driving or operating machinery until you know how Silinor 100 affects you.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
descriptionBrief Description


Type 2 diabetes mellitus


May be taken with or without food.

Adult Dose

Oral Type 2 diabetes mellitus Adult: 100 mg once daily. Hepatic impairment Mild to moderate impairment: Dose adjustment not necessary Severe impa... View More

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 50 mg PO qDay CrCl <30 mL/min: 25 mg PO qDay ESRD: 25 mg PO qDay ... View More


Hypersensitivity reactions such as anaphylaxis, angioedema, and exfoliative skin conditions including Stevens-Johnson syndrome can occur. Type 1 diabete... View More

Mode of Action

Sitagliptin inhibits dipeptidyl peptidase IV (DPP-IV), resulting in prolonged active incretin levels. Incretin hormones increases insulin synthesis and ... View More


Patient w/ type 1 diabetes, history of angioedema. Not intended for the treatment of diabetic ketoacidosis. Moderate and severe renal impairment. Pregna... View More

Side Effect

1-10% Nasopharyngitis (5%),Diarrhea (4%),Headache (3.6%),Constipation (3%),Peripheral edema (2%),Nausea (2%),Pharyngitis (1%),Osteoarthritis (1%),URI (... View More


Increased risk of hypoglycaemia when used in combination w/ sulfonylureas or insulin.

Alternative brand for Silinor 100
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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