Introduction
Siloflo 8 is an alpha adrenergic antagonist that is used in the treatment of benign prostatic hyperplasia. It helps to relieve symptoms like difficulty in passing urine. However, it does not decrease the size of the prostate.
Siloflo 8 is advised to take it in a dose and duration as per prescription. It should be taken with food, but take at the same time regularly. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.
Some common side effects of this medicine are headache and tiredness. It may also lead to blurry vision or dizziness, so it is advised to avoid driving while on the medication. If any of the side effects persist or bother you, you must consult the doctor without delay.
Simple lifestyle changes can help you manage your symptoms better. Try to urinate as soon as you feel the urge, however, never strain or push to empty your bladder. You should avoid drinking caffeinated or alcoholic drinks at night and a few hours before going to bed or going out.
Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment. If you have to undergo eye surgery due to cataract or glaucoma than inform your eye doctor about the usage of this medicine. Patients with liver or kidney disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor's advice.
Uses of Siloflo 8
- Benign prostatic hyperplasia
Side effects of Siloflo 8
Common
- Retrograde ejaculation
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Dizziness
- Headache
- Nasal congestion (stuffy nose)
- Diarrhea
How to use Siloflo 8
Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Siloflo 8 is to be taken with food.
How Siloflo 8 works
Siloflo 8 is an alpha blocker. It works by relaxing muscle around the bladder exit and prostate gland so urine is passed more easily.
What if you forget to take Siloflo 8?
If you miss a dose of Siloflo 8, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Indication
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Adult Dose
Benign Prostatic Hyperplasia
Adults
PO 8 mg once daily with a meal.
Hepatic Impairment
Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary
Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)
Renal Dose
Renal Impairment
CrCl <50 mL/min: Dose adjustment not necessary
CrCl 30-50 mL/min: 4 mg PO qDay
CrCl <30 mL/min: Contraindicated
Contraindication
Hypersensitivity.
Mode of Action
Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Precaution
Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).
Side Effect
>10%
Retrograde ejaculation (28%)
1-10%
Diarrhea (3%),Headache (2%),Insomnia ((1-2%),Dizziness (3%),Orthostatic hypotension (3%; increased in patients >65 years),Nasopharyngitis (2%),Nasal congestion (2%),Sinusitis (1-2%)
Interaction
Ketoconazole, digoxin.