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Delta Pharma Limited
Generic: Diltiazem Hydrochloride
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descriptionSafety Advices
Caution is advised when consuming alcohol with Tizem. Please consult your doctor.
Tizem may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing b... View More
Tizem is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harm... View More
Tizem may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Tizem is safe to use in patients with kidney disease. No dose adjustment of Tizem is recommended. However, talk to your doctor if you have any underlyin... View More
Tizem should be used with caution in patients with liver disease. Dose adjustment of Tizem may be needed. Please consult your doctor.
descriptionMedical Overview


Tizem is used to treat angina (heart-related chest pain), high blood pressure and some types of irregular heartbeats (arrhythmia). It is known as a calc... View More

Uses of Tizem

  • Hypertension (high blood pressure)
  • Angina (heart-related chest pain)
  • Arrhythmia

Side effects of Tizem

  • Headache
  • Constipation
  • Dizziness
  • Fatigue
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Nausea
  • Rash

How to use Tizem

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tizem may be taken with or... View More

How Tizem works

Tizem is a calcium channel blocker. It blocks the action of calcium on the heart and blood vessels, thereby widening the blood vessels and allowing more... View More

quick tipsQuick Tips
  • Dilzem 30 Tablet CR slows down the heartbeat and allows the blood vessels in the body to relax.
  • This helps prevent angina attacks (chest pain caused by heart disease), certain abnormal heart rhythms, stroke and heart attack.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.... View More
  • It is best to avoid drinking alcohol while taking Dilzem 30 Tablet CR as it may make the side effects worse.
  • Do not stop taking it suddenly without talking to your doctor first.
descriptionBrief Description


Supraventricular tachycardia, Hypertension, Angina, Atrial fibrillation, Arrhythmias, Atrial flutter


May be taken with or without food. The capsules should be swallowed whole with a drink of water. They should not be crushed or chewed

Adult Dose

Angina Conventional tablet: 30 mg PO q6hr; increased every 1 or 2 days until angina controlled (usually 180-360 mg/day PO divided q6-8hr); not to excee... View More

Renal Dose

Renal Impairment Use caution


Sick-sinus syndrome; 2nd or 3rd ° AV block; porphyria. Severe congestive cardiac failure; marked bradycardia. Pregnancy and lactation.

Mode of Action

Diltiazem relaxes coronary vascular smooth muscles by inhibiting influx of calcium ions during depolarisation of the vascular smooth muscles and myocard... View More


Elderly. Hepatic or renal impairment; impaired left ventricular function; prolonged AV periods; DM; hypotension. Avoid abrupt withdrawal and long-term u... View More

Side Effect

>10% Edema (2-15%),Headache (5-12%) 1-10% Dizziness (3-10%),AV block (2-8%),Peripheral edema (2-8%),Bradyarrhythmia (2-6%),Headache (1-5%),Hypotens... View More

Pregnancy Category Note

Pregnancy category: C Lactation: Drug enters breast milk; because of risk for serious adverse reactions in nursing infants from diltiazem, a decision... View More


Increased AV blocking effect w/ clonidine. May increase serum levels of statins (e.g. atorvastatin, lovastatin), carbamazepine, phenytoin. May increase ... View More

Alternative brand for Tizem
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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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