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Avifix250mg

Tablet
rx_reqRequire Prescription
Beximco Pharmaceuticals Ltd.
Generic: Nelfinavir
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40.50
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45.00
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descriptionSafety Advices
AlcoholAlcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Avifix. Please consult your doctor.
PregnancyPregnancy
SAFE IF PRESCRIBED
Avifix is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there ... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Avifix is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether Avifix alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and reac... View More
KidneyKidney
SAFE IF PRESCRIBED
Avifix is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Avifix may not be needed in thes... View More
LiverLiver
CAUTION
Avifix should be used with caution in patients with liver disease. Dose adjustment of Avifix may be needed. Please consult your doctor. Use of Avifix is... View More
descriptionMedical Overview

Introduction

Avifix is an antiviral or antiretroviral medicine. It is used in the treatment of HIV infection. It stops the virus from producing new viruses and clear... View More

Uses of Avifix

  • HIV infection

Side effects of Avifix

Common
  • Rash
  • Headache
  • Dizziness
  • Vomiting
  • Crystals in urine
  • Nausea
  • Abdominal pain
  • Indigestion
  • Paresthesia (tingling or pricking sensation)
  • Throat pain
  • Increased liver enzymes
  • Diarrhea
  • Blood in urine
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Cough
  • Taste change
  • Hypercholesterolemia (high cholesterol)
  • Increased triglyceride level in blood
  • Protein in urine

How to use Avifix

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avifix is to be taken with... View More

How Avifix works

Avifix is an anti-HIV medication. It works by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This s... View More

quick tipsQuick Tips
  • Avifix should be taken with food.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of t... View More
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description

Indication

HIV infection

Administration

Should be taken with food.

Adult Dose

Oral HIV infection Adult: Combined with other antiretrovirals: 1.25 g bid or 0.75 g tid. Hepatic Impairment Mild impairment (Child-Pugh class A): ... View More

Child Dose

Oral HIV infection Child: Combined with other antiretrovirals: 2-13 yr: 45-55 mg/kg bid or 25-35 mg/kg tid. Max: 0.75 g tid. Max Dosage: Child: 0.7... View More

Renal Dose

Renal Impairment Dose adjustment not necessary

Contraindication

Hypersensitivity; lactation.

Mode of Action

Nelfinavir is a selective, competitive, reversible HIV protease inhibitor. It inhibits HIV-1 protease preventing the cleavage of the gag-pol polyprotein... View More

Precaution

Pregnancy. Hepatic and renal impairment; haemophilia A or B; diabetes. Monitor for signs of lipodystrophy. Lactation: HIV+ women are advised not to b... View More

Side Effect

>10% Diarrhea (14-20%) 1-10% Nausea (3-7%),Flatulence (1-5%),Abdominal pain (1%),Anemia (1%),Allergic reaction (1%),Impaired concentration (1%),Lip... View More

Interaction

Reduced levels/effects with antacids, phenobarbital, carbamazepine, aminoglutethimide, phenytoin, rifampicin, nafcillin, nevirapine, omeprazole, nevirap... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More