Introduction
Avifix is an antiviral or antiretroviral medicine. It is used in the treatment of HIV infection. It stops the virus from producing new viruses and clear... View More
Uses of Avifix
Side effects of Avifix
How to use Avifix
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avifix is to be taken with... View More
How Avifix works
Avifix is an anti-HIV medication. It works by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This s... View More
Indication
HIV infection
Administration
Should be taken with food.
Adult Dose
Oral HIV infection Adult: Combined with other antiretrovirals: 1.25 g bid or 0.75 g tid. Hepatic Impairment Mild impairment (Child-Pugh class A): ... View More
Child Dose
Oral HIV infection Child: Combined with other antiretrovirals: 2-13 yr: 45-55 mg/kg bid or 25-35 mg/kg tid. Max: 0.75 g tid. Max Dosage: Child: 0.7... View More
Renal Dose
Renal Impairment Dose adjustment not necessary
Contraindication
Hypersensitivity; lactation.
Mode of Action
Nelfinavir is a selective, competitive, reversible HIV protease inhibitor. It inhibits HIV-1 protease preventing the cleavage of the gag-pol polyprotein... View More
Precaution
Pregnancy. Hepatic and renal impairment; haemophilia A or B; diabetes. Monitor for signs of lipodystrophy. Lactation: HIV+ women are advised not to b... View More
Side Effect
>10% Diarrhea (14-20%) 1-10% Nausea (3-7%),Flatulence (1-5%),Abdominal pain (1%),Anemia (1%),Allergic reaction (1%),Impaired concentration (1%),Lip... View More
Interaction
Reduced levels/effects with antacids, phenobarbital, carbamazepine, aminoglutethimide, phenytoin, rifampicin, nafcillin, nevirapine, omeprazole, nevirap... View More
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More