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Safety Advices
বাংলা
English
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Avifix. Please consult your doctor.
SAFE IF PRESCRIBED
Avifix is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Avifix is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CONSULT YOUR DOCTOR
It is not known whether Avifix alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
SAFE IF PRESCRIBED
Avifix is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Avifix may not be needed in these patients. Please consult your doctor.
CAUTION
Avifix should be used with caution in patients with liver disease. Dose adjustment of Avifix may be needed. Please consult your doctor.
Use of Avifix is not recommended in patients with moderate and severe liver disease.
Medicine Overview of Avifix 250mg Tablet
Introduction
Avifix is an antiviral or antiretroviral medicine. It is used in the treatment of HIV infection. It stops the virus from producing new viruses and clears up your infection. Avifix should be taken with food, as this increases the absorption of the medicine into the body. You should take it in the dose and duration as advised by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too...
... Show moreUses of Avifix
- HIV infection
Side effects of Avifix
Common
- Rash
- Headache
- Dizziness
- Vomiting
- Crystals in urine
- Nausea
- Abdominal pain
- Indigestion
- Paresthesia (tingling or pricking sensation)
- Throat pain
- Increased liver enzymes
- Diarrhea
- Blood in urine
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Cough
- Taste change
- Hypercholesterolemia (high cholesterol)
- Increased triglyceride level in blood
- Protein in urine
How to use Avifix
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avifix is to be taken with food.
How Avifix works
Avifix is an anti-HIV medication. It works by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses.
Quick Tips
- Avifix should be taken with food.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Brief Description
Indication
HIV infection
Administration
Should be taken with food.
Adult Dose
Oral
HIV infection
Adult: Combined with other antiretrovirals: 1.25 g bid or 0.75 g tid.
Hepatic Impairment
Mild impairment (Child-Pugh class A): Dose adjustment not necessary
Severe impairment (Child-Pugh Class B or C): Not recommended
Child Dose
Oral
HIV infection
Child: Combined with other antiretrovirals:
2-13 yr: 45-55 mg/kg bid or 25-35 mg/kg tid. Max: 0.75 g tid.
Max Dosage: Child: 0.75 g tid.
Renal Dose
Renal Impairment
Dose adjustment not necessary
Contraindication
Hypersensitivity; lactation.
Mode of Action
Nelfinavir is a selective, competitive, reversible HIV protease inhibitor. It inhibits HIV-1 protease preventing the cleavage of the gag-pol polyprotein resulting in the production of noninfectious virus.
Precaution
Pregnancy. Hepatic and renal impairment; haemophilia A or B; diabetes. Monitor for signs of lipodystrophy.
Lactation: HIV+ women are advised not to breastfeed
Side Effect
>10%
Diarrhea (14-20%)
1-10%
Nausea (3-7%),Flatulence (1-5%),Abdominal pain (1%),Anemia (1%),Allergic reaction (1%),Impaired concentration (1%),Lipodystrophy (1%),Metabolic acidosis (1%),Rash (1-3%),Leukopenia (1%),Thrombocytopenia (1%),Weakness (1%)
<1%
QTc prolongation,Torsades de pointes,Diabetes mellitus, new onset and exacerbation,Hyperglycemia
Interaction
Reduced levels/effects with antacids, phenobarbital, carbamazepine, aminoglutethimide, phenytoin, rifampicin, nafcillin, nevirapine, omeprazole, nevirapine. Increased serum levels/effects with azole antifungal agents, cimetidine, efavirenz. Increased serum levels/effects of azithromycin, calcium channel blockers, clarithromycin, corticosteroids (e.g. fluticasone), mirtazapine, nateglinide, nefazodone, ciclosporin, sirolimus, tacrolimus, venlafaxine, eplerinone, fentanyl, atorvastatin, phosphodiesterase-5 (PDE-5) inhibitors, rifabutin, trazodone, TCAs. Reduced serum levels/effects of hormonal contraceptives, methadone, theophylline derivatives.
Potentially Fatal: Increased serum levels/toxicity of amiodarone, cisapride, pimozide, midazolam, triazolam, ergot alkaloids, lovastatin, simvastatin, quinidine.
ব্যবসার জন্য পাইকারি দামে পণ্য কিনতে রেজিস্টেশন করুন
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