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Tupime IV/IM1gm/vial

Injection
rx_reqRequire Prescription
Kemiko Pharmaceuticals Ltd.
Generic: Cefepime
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Tupime IV/IM does not cause any harmful side effects.
PregnancyPregnancy
SAFE IF PRESCRIBED
Tupime IV/IM is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, ... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Tupime IV/IM is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is n... View More
DrivingDriving
CONSULT YOUR DOCTOR
It is not known whether Tupime IV/IM alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate an... View More
KidneyKidney
CAUTION
Tupime IV/IM should be used with caution in patients with kidney disease. Dose adjustment of Tupime IV/IM may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Tupime IV/IM is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tupime IV/IM may not be nee... View More
descriptionMedical Overview

Introduction

Tupime IV/IM is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the skin, lungs, stomach, urinary tract, and bloo... View More

Uses of Tupime IV/IM

  • Bacterial infections

Side effects of Tupime IV/IM

Common
  • Rash
  • Itching
  • Nausea
  • Vomiting
  • Headache
  • Fever
  • Diarrhea

How to use Tupime IV/IM

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tupime IV/IM works

Tupime IV/IM is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them ... View More

What if you forget to take Tupime IV/IM?

If you miss a dose of Tupime IV/IM, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to y... View More

quick tipsQuick Tips
  • Your doctor has prescribed Tupime IV/IM to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder ... View More
  • Discontinue Tupime IV/IM and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
  • Avoid consuming alcohol while taking Tupime IV/IM as it may cause increased side effects.
descriptionBrief Description

Indication

Skin and skin structure infections, Urinary tract infection, Nosocomial pneumonia, Multiple drug resistant pneumonia, Neutropenia

Administration

Reconstitution: IV infusion: Add 5 mL, 10 mL, or 10 mL of a compatible IV soln to a vial labeled as containing 500 mg, 1 g, or 2 g, respectively, to pro... View More

Adult Dose

Adult: IV UTI 0.5-1 g 12 hrly for 7-10 days. Empirical therapy for febrile neutropenia 2 g 8 hrly for 7 days or until resolution of neutropenia. Mod... View More

Child Dose

Child: IV, IM 100 mg/kg/day q12h 150 mg/kg/day empiric therapy of fever with neutropenia q8h 2 mth - 16 yr: >40 kg: 50 mg/kg every 12 hr for 7-10 da... View More

Renal Dose

Renal impairment: Haemodialysis: 1 g on the 1st day of treatment, followed by 0.5 g 24 hrly; dose should be given after haemodialysis on dialysis days... View More

Contraindication

Hypersensitivity to cefepime or other cephalosporins.

Mode of Action

Cefepime is a 4th generation cephalosporin which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall by binding t... View More

Precaution

Renal impairment; history of penicillin or cephalosporin allergy; lactation, pregnancy. Caution when used in patients with history of GI diseases, espec... View More

Side Effect

>10% Positive Coombs test result without hemolysis (16%) 1-10% Rash (1-4%),Elevated alanine aminotransferase (3%),Hypophosphatemia (3%),Diarrhea (<... View More

Pregnancy Category Note

Pregnancy category: B Lactation: Drug enters breast milk; use with caution

Interaction

Increased potential for nephrotoxicity and ototoxicity of aminoglycosides. Increased risk of nephrotoxicity w/ potent diuretics (e.g. furosemide).

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More

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