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Beacon Pharmaceuticals Ltd.
Generic: Zonisamide
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descriptionSafety Advices
Xonimide may cause excessive drowsiness with alcohol.
Xonimide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developin... View More
Xonimide is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Xonimide may cause side effects which could affect your ability to drive. As Xonimide may affect your concentration, ability to react/respond, and may m... View More
Xonimide should be used with caution in patients with severe kidney disease. Dose adjustment of Xonimide may be needed. Please consult your doctor.
There is limited information available on the use of Xonimide in patients with liver disease. Please consult your doctor. Use of Xonimide is not recomme... View More
descriptionMedical Overview


Xonimide is an anti-epileptic medicine used to treat seizures in epilepsy. It can be used by itself to treat adults or along with other medicines to tre... View More

Uses of Xonimide

  • Epilepsy/Seizures

Side effects of Xonimide

  • Dizziness
  • Loss of appetite
  • Memory impairment
  • Drowsiness
  • Impaired concentration
  • Altered walking
  • Impaired coordination
  • Anger

How to use Xonimide

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xonimide may be taken with... View More

How Xonimide works

Xonimide is an antiepileptic medication. It prevents seizures in patients with epilepsy by suppressing the abnormal and excessive activity of the nerve ... View More

What if you forget to take Xonimide?

If you miss a dose of Xonimide, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
  • Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Drink plenty of water while taking Xonimide to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stom... View More
  • It may cause loss of appetite and weight. Monitor your weight regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
descriptionBrief Description


Adjunct in partial seizures, Monotherapy for partial seizures with or without secondary generalisation


May be taken with or without food.

Adult Dose

Oral Adjunct in partial seizures Adult: Initially, 50 mg daily in 2 divided doses, increase to 100 mg daily after 1 wk. Thereafter, may further increa... View More

Child Dose

Oral Adjunct in partial seizures Child: >6 yr Initially, 1 mg/kg once daily for 1 wk, may increase by increments of 1 mg/kg at wkly interval. Usual ma... View More

Renal Dose

Renal impairment: GFR ?50 mL/min: Slower dosage titration may be needed. GFR <50 mL/min: Not recommended.


Hypersensitivity to zonisamide or sulfonamides

Mode of Action

Zonisamide is a benzisoxazole derivative anticonvulsant containing sulfonamide. It may act on voltage sensitive Na and Ca channels, thereby affecting ne... View More


Patient at risk of nephrolithiasis. Avoid abrupt withdrawal. Renal or hepatic impairment. Childn. Pregnancy and lactation. Patient Counselling Increase ... View More

Side Effect

>10% Somnolence (17%) Anorexia (13%) Dizziness (13%) 1-10% Headache (10%) Nausea (9%) Agitation (9%) Abdominal pain (6%) Ataxia (6%) Confusi... View More


Reduced plasma concentration w/ phenytoin, phenobarbital, carbamazepine. Increased risk of metabolic acidosis w/ carbonic anhydrase inhibitors (e.g. ace... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More