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Generic: Lisinopril
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descriptionSafety Advices
It is unsafe to consume alcohol with Zestril.
Zestril is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in s... View More
Zestril is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Zestril may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Zestril should be used with caution in patients with kidney disease. Dose adjustment of Zestril may be needed. Please consult your doctor. Regular monit... View More
Zestril should be used with caution in patients with liver disease. Dose adjustment of Zestril may be needed. Please consult your doctor. Inform your do... View More
descriptionMedical Overview


Zestril belongs to a group of medicines known as angiotensin converting enzyme (ACE) inhibitor. It is widely used to treat high blood pressure and heart... View More

Uses of Zestril

  • Hypertension (high blood pressure)
  • Prevention of heart attack and stroke
  • Heart failure

Side effects of Zestril

  • Decreased blood pressure
  • Cough
  • Increased potassium level in blood
  • Fatigue
  • Weakness
  • Dizziness

How to use Zestril

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zestril may be taken with ... View More

How Zestril works

Zestril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more... View More

What if you forget to take Zestril?

If you miss a dose of Zestril, skip it and continue with your normal schedule. Do not double the dose.

quick tipsQuick Tips
  • Zestril can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime ... View More
  • Let your doctor know about any cough, or throat irritation that does not go away.
  • It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
descriptionBrief Description


Heart failure, Myocardial infarction, Diabetic nephropathy, Hypertension


May be taken with or without food.

Adult Dose

Oral Hypertension Adult: Initially, 10 mg/day, 1st dose given preferably at bedtime to avoid precipitous fall in BP. Patient w/ renovascular HTN, volu... View More

Child Dose

Oral Hypertension Child: >6 yr Initially, 0.07 mg/kg, up to 5 mg once daily.

Renal Dose

Hypertension Renal impairment: Adult: CrCl <10 mL/min or on dialysis: Initially, 2.5 mg once daily. CrCl 10-30 mL/min: Initially, 2.5-5 mg once daily. ... View More


History of angioedema related to previous treatment with ACE inhibitors, hereditary or idiopathic angioedema. Bilateral renal artery stenosis. Pregnancy... View More

Mode of Action

Lisinopril competitively inhibits ACE from converting angiotensin I to angiotensin II (a potent vasoconstrictor) resulting in increased plasma renin act... View More


Hypovolaemia, hyperkalaemia, collagen vascular disease, valvular stenosis; before, during or immediately after anaesthesia, preexisting renal insufficie... View More

Side Effect

>10% Dizziness (5-12%) 1-10% Cough (4-9%),Headache (4-6%),Hyperkalemia (2-5%),Diarrhea (3-4%),Hypotension (1-4%),Chest pain (3%),Fatigue (3%),Nause... View More


May enhance hypotensive effect w/ diuretics. May increase risk of renal function deterioration and decrease antihypertensive effect w/ NSAIDs. May incre... View More


The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More