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Zofra ODT 44mg

Tablet
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Eskayef Pharmaceuticals Ltd.
Generic: Ondansetron
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4.50
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5.00
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Zofra ODT 4 does not cause any harmful side effects.
PregnancyPregnancy
SAFE IF PRESCRIBED
Zofra ODT 4 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, t... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Zofra ODT 4 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.... View More
DrivingDriving
SAFE
Zofra ODT 4 does not usually affect your ability to drive.
KidneyKidney
SAFE IF PRESCRIBED
Zofra ODT 4 is safe to use in patients with kidney disease. No dose adjustment of Zofra ODT 4 is recommended. However, inform your doctor if you have an... View More
LiverLiver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zofra ODT 4 in patients with liver disease. Please consult your doctor.
descriptionMedical Overview

Introduction

Zofra ODT 4 is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used... View More

Uses of Zofra ODT 4

  • Nausea
  • Vomiting

Side effects of Zofra ODT 4

Common
  • Constipation
  • Diarrhea
  • Fatigue
  • Headache

How to use Zofra ODT 4

Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow... View More

How Zofra ODT 4 works

Zofra ODT 4 is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomi... View More

What if you forget to take Zofra ODT 4?

If you miss a dose of Zofra ODT 4, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to yo... View More

quick tipsQuick Tips
  • You have been prescribed Ondace 4mg Tablet MD for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • Unlike some other nausea medicines, the side effects for Ondace 4mg Tablet MD are relatively mild.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
descriptionBrief Description

Indication

Prevention of nausea-vomiting associated with chemotherapy, Prevention of nausea & vomiting associated with radiotherapy, Prevention of post-operative n... View More

Administration

May be taken with or without food. Reconstitution: Prior to IV infusion, dilute in 50 mL dextrose 5% inj or normal saline.

Adult Dose

Oral Adult: Prevention of nausea & vomiting associated with chemotherapy: Highly emetogenic chemotherapy: 24 mg once 30 minutes before start of sing... View More

Child Dose

Oral Moderate emetogenic cancer chemotherapy: Child (4-11 years): 4 mg tablet should be taken 30 minutes before the start of chemotherapy. The other... View More

Renal Dose

Renal impairment: Dose adjustment not necessary

Contraindication

Use with apomorphine (profound hypotension).

Mode of Action

Ondansetron antagonises selective 5-HT3-receptor, blocking serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trig... View More

Precaution

May mask progressive ileus and/or gastric distension. Severe hepatic impairment. Pregnancy and lactation. Monitoring Parameters ECG monitoring of patien... View More

Side Effect

>10% Headache (9-27%),Malaise/fatigue (9-13%),Constipation (6-11%) 1-10% Hypoxia (9%),Drowsiness (8%),Diarrhea (2-7%),Dizziness (7%),Fever (2-8%),G... View More

Interaction

May reduce analgesic effect of tramadol. Rifampicin and other CYP3A4 inducers may reduce levels/effects of ondansetron. Concomitant use of QT-prolonging... View More

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descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More