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Zolibac500mg/5ml

Injection
rx_reqRequire Prescription
Square Pharmaceuticals Ltd.
Generic: Cefazolin
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descriptionSafety Advices
AlcoholAlcohol
SAFE
Consuming alcohol with Zolibac does not cause any harmful side effects.
PregnancyPregnancy
SAFE IF PRESCRIBED
Zolibac is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there... View More
BreastfeedingBreastfeeding
SAFE IF PRESCRIBED
Zolibac is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not ha... View More
DrivingDriving
UNSAFE
Zolibac may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyKidney
CAUTION
Zolibac should be used with caution in patients with kidney disease. Dose adjustment of Zolibac may be needed. Please consult your doctor.
LiverLiver
SAFE IF PRESCRIBED
Zolibac is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Zolibac may not be needed in the... View More
descriptionMedical Overview

Introduction

Zolibac is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (eg. pneumonia), ear, urin... View More

Uses of Zolibac

  • Bacterial infections

Side effects of Zolibac

Common
  • Rash
  • Injection site reactions (pain, swelling, redness)
  • Allergic reaction
  • Nausea
  • Indigestion
  • Diarrhea

How to use Zolibac

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zolibac works

Zolibac is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to su... View More

What if you forget to take Zolibac?

If you miss a dose of Zolibac, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your r... View More

quick tipsQuick Tips
  • Your doctor has prescribed Zolibac to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder ... View More
  • Discontinue Zolibac and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your sto... View More
  • Avoid consuming alcohol while taking Zolibac as it may cause increased side effects.
descriptionBrief Description

Indication

Infections With Gram-Positive Cocci, Mild-to-Moderate Cholecystitis, Uncomplicated Urinary Tract Infection, Prophylaxis against surgical infection, Endo... View More

Administration

IV Preparation Reconstitute 500 mg or 1 g with 2 mL or 2.5 mL SWI, respectively, to provide solutions containing approximately 225 or 330 mg/mL IV p... View More

Adult Dose

Parenteral Susceptible infections Adult: Mild: 0.25-0.5 g 8 hrly. Moderate to severe: 0.5-1 g 6-8 hrly. Severe, life-threatening: 1-1.5 g 6 hrly. ... View More

Child Dose

Parenteral Susceptible infections Child: >1 yr 25-50 mg/kg daily in 3 or 4 divided doses to be given by deep IM inj, slow IV inj over 3-5 min, or inte... View More

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <10 Half the usual dose 18-24 hrly. 11-34 Half the usual dose 12 hrly. 35-54 Usual dose at int... View More

Contraindication

Hypersensitivity to cephalosporins.

Mode of Action

Cefazolin binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bact... View More

Precaution

Patient w/ history of hypersensitivity to penicillins, GI disease particularly colitis, seizure disorder. Renal impairment. Pregnancy and lactation. Mon... View More

Side Effect

Diarrhoea, oral candidiasis, vomiting, nausea, stomach cramps, anorexia; eosinophilia, itching, drug fever, skin rash, Stevens-Johnson syndrome; neutrop... View More

Pregnancy Category Note

Pregnancy category: B Lactation: Drug excreted in breast milk; use with caution (American Academy of Pediatrics committee states that drug is compati... View More

Interaction

May enhance the anticoagulant effect of vit K antagonists (e.g. warfarin). May diminish the therapeutic effect of Na picosulfate, BCG and typhoid vaccin... View More

descriptionDisclaimer

The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not... View More